WO2023031788 - T7 RNA POLYMERASE VARIANTS FOR RNA SYNTHESIS
National phase entry:
Publication Number
WO/2023/031788
Publication Date
09.03.2023
International Application No.
PCT/IB2022/058118
International Filing Date
30.08.2022
Title **
[English]
T7 RNA POLYMERASE VARIANTS FOR RNA SYNTHESIS
[French]
VARIANTS D'ARN POLYMÉRASE T7 POUR LA SYNTHÈSE D'ARN
Applicants **
GLAXOSMITHKLINE BIOLOGICALS SA
Inventors
DORR, Brent M.
JELIAZKOV, Jeliazko
MELBY, Joel
RUDRAPPA, Deepak
VAIDYA, Nilesh
Priority Data
63/239,458
01.09.2021
US
63/395,070
04.08.2022
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
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| Number of Pages with Drawings | * |
| Pages of Specification | * |
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| Number of Office Actions | * |
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International Searching Authority |
EPO
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 3084 | |
| EPO | Filing, Examination, Granting | 18099 | |
| Japan | Filing, Examination, Granting | 2616 | |
| South Korea | Filing, Examination, Granting | 3046 | |
| USA | Filing, Examination, Granting | 11390 |
Total:
38,235
The term for entry into the National Phase has expired. This quotation is for informational purposes only
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Abstract[English]
The present disclosure provides T7 RNA polymerase variants, the use of which increases transcription efficiency and improves the quality and yield of the enzyme. Also provided are polynucleotides encoding the T7 RNA polymerase variants, host cells capable of expressing the T7 RNA polymerase variants, and methods of using the T7 RNA polymerase variants for high-efficiency transcription.[French]
La présente invention concerne des variants d'ARN polymérase T7, l'utilisation de ceux-ci augmentant l'efficacité de transcription et améliorant la qualité et le rendement de l'enzyme. L'invention concerne également des polynucléotides codant pour les variants d'ARN polymérase T7, des cellules hôtes capables d'exprimer les variants d'ARN polymérase T7, ainsi que des procédés d'utilisation des variants d'ARN polymérase T7 pour une transcription à haut rendement.