WO2023021427 - FREEZE-DRYING OF LIPID NANOPARTICLES (LNPS) ENCAPSULATING RNA AND FORMULATIONS THEREOF
National phase entry:
Publication Number
WO/2023/021427
Publication Date
23.02.2023
International Application No.
PCT/IB2022/057683
International Filing Date
16.08.2022
Title **
[English]
FREEZE-DRYING OF LIPID NANOPARTICLES (LNPS) ENCAPSULATING RNA AND FORMULATIONS THEREOF
[French]
LYOPHILISATION DE NANOPARTICULES LIPIDIQUES (LNP) ENCAPSULANT DE L'ARN ET LEURS FORMULATIONS
Applicants **
GLAXOSMITHKLINE BIOLOGICALS SA
Rue de I'Institut 89
1300 Rixensart, BE
Inventors
LODAYA, Rushit
c/o Glaxosmithkline
14200 Shady Grove Road
Rockville, Maryland 20850, US
POHLHAUS, Patrick
c/o Glaxosmithkline
14200 Shady Grove Road
Rockville, Maryland 20850, US
ZECCA, Elizabeth
c/o Glaxosmithkline
14200 Shady Grove Road
Rockville, Maryland 20850, US
ZHANG, Jinjin
c/o Glaxosmithkline
14200 Shady Grove Road
Rockville, Maryland 20850, US
PADILLA, Adora
c/o Glaxosmithkline
14200 Shady Grove Road
Rockville, Maryland 20850, US
BOURLÈS, Erwan
c/o Glaxosmithkline Biologicals SA
Rue de l'Institut 89
1300 Rixensart, BE
ENERT, Julie
c/o Glaxosmithkline Biologicals SA
Rue de l'Institut 89
1300 Rixensart, BE
Priority Data
63/233,517
16.08.2021
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
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International Searching Authority |
EPO
* |
| Applicant's Legal Status |
Legal Entity
* |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Translation |
|
Recalculate
* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing | 2524 | |
| EPO | Filing, Examination | 13066 | |
| Japan | Filing | 588 | |
| South Korea | Filing | 574 | |
| USA | Filing, Examination | 8210 |
Total: 24962 USD
The term for entry into the National Phase has expired. This quotation is for informational purposes only
Abstract[English]
Compositions and methods are provided for stabilization of RNA encapsulated by lipid nanoparticles during lyophilization. Novel lyophilization processes are provided. These techniques may be used to prevent the need for cold chain storage.[French]
L'invention concerne des compositions et des procédés de stabilisation d'ARN encapsulé par des nanoparticules lipidiques en cours de lyophilisation. L'invention concerne de nouveaux procédés de lyophilisation. Ces techniques peuvent être utilisées pour empêcher la nécessité d'un stockage en chaîne du froid.