WO2023017393 - PROCESS FOR THE PREPARATION OF OLAPARIB, AND CRYSTALLINE FORM THEREOF

National phase entry:
Publication Number WO/2023/017393
Publication Date 16.02.2023
International Application No. PCT/IB2022/057356
International Filing Date 08.08.2022
Title **
[English] PROCESS FOR THE PREPARATION OF OLAPARIB, AND CRYSTALLINE FORM THEREOF
[French] PROCÉDÉ DE PRÉPARATION D'OLAPARIB ET SA FORME CRISTALLINE
Applicants **
GLENMARK LIFE SCIENCES LIMITED Glenmark House, HDO- Corporate Building, Wing-A, B. D. Sawant Marg, Chakala, Andheri (East), Mumbai 400099, Maharashtra, IN
Inventors
PALLE, Venkata Raghavendra Charyulu Bungalow 24, Gera Green Ville, Survey no. 64, Grant Road, Kharadi, Pune, Maharashtra, 411014, IN
PATEL, Pratik R. 7, Anand Vihar, Gotri Vasna Road, Gotri, Vadodara, Gujarat, 390021, IN
ALI, Nasir Flat no.1604 Maxima-E, Casa bella Gold, Kalyan Shil Road, Palava, Dombivali E, Thane, Maharashtra, 421204, IN
SHELKE, Shivaji Haribhau B-104, Beverlee, Casa Rio, Kalyan Shil Road, Palava, Dombivali E, Thane Maharashtra, 421204, IN
LAD, Sachin Mahadeo A2/206, Raj Residency, GB Road, Kasarvadavali, Thane west Maharashtra, 400607, IN
PATLE, Girish Tilakchand Flat No.1204, Sidhivinayak orchid, Plot no.14, Sector 20, Sion-Pune Highway, Kalamboli-Panvel. Maharashtra, 410218, IN
SHANMUGHASAMY, Raj Mahendra Plot.No.35, Silver castle, Chinna Elasagiri, Hosur, Tamilnadu, 635126, IN
YADAV, Premkumar Ramraj 105, Shree Ashapura Residency, Plot No A/5/1, Khanda Colony, Sector-7, New Panvel, Maharashtra, 410206, IN
Priority Data
202121035948   09.08.2021   IN
202221012208   07.03.2022   IN
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Quotation for National Phase entry

Country StagesTotal
China Filing1523
EPO Filing, Examination9801
Japan Filing587
South Korea Filing606
USA Filing, Examination8510
MasterCard Visa

Total: 21027

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] The present invention relates to a process for the preparation of olaparib. The present invention also relates to a novel crystalline form of olaparib, and a process for its preparation. Further, the present invention also relates to a pharmaceutical composition containing a therapeutically effective amount of the novel crystalline form of olaparib. Also, the present invention relates to improved processes for the preparation of crystalline form H and crystalline form A of olaparib.[French] La présente invention concerne un procédé de préparation d'olaparib. La présente invention concerne également une nouvelle forme cristalline d'olaparib, et un procédé pour sa préparation. En outre, la présente invention concerne également une composition pharmaceutique contenant une quantité thérapeutiquement efficace de la nouvelle forme cristalline d'olaparib. La présente invention concerne également des procédés améliorés pour la préparation de la forme cristalline H et de la forme cristalline A d'olaparib.
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