WO2023012669 - BIOPHARMACEUTICAL COMPOSITIONS AND STABLE ISOTOPE LABELING PEPTIDE MAPPING METHOD

National phase entry:
Publication Number WO/2023/012669
Publication Date 09.02.2023
International Application No. PCT/IB2022/057173
International Filing Date 02.08.2022
Title **
[English] BIOPHARMACEUTICAL COMPOSITIONS AND STABLE ISOTOPE LABELING PEPTIDE MAPPING METHOD
[French] COMPOSITIONS BIOPHARMACEUTIQUES ET PROCÉDÉ DE CARTOGRAPHIE PEPTIDIQUE DE MARQUAGE ISOTOPIQUE STABLE
Applicants **
GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED GSK Medicines Research Centre Gunnels Wood Road Stevenage SG1 2NY, GB
Inventors
DAVIS, Tyler Keith 1250 S Collegeville Rd Collegeville, Pennsylvania 19426, US
SCHUESSLER, Hillary Amber 1250 S Collegeville Rd Collegeville, Pennsylvania 19426, US
Priority Data
63/228,951   03.08.2021   US
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Quotation for National Phase entry

Country StagesTotal
China Filing2407
EPO Filing, Examination15111
Japan Filing593
South Korea Filing575
USA Filing, Examination12110
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Total: 30796

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] Disclosed herein are stable isotope labeling (SIL) peptide mapping methods for accurate and sensitive conjugation site quantitation. Also disclosed herein are compositions comprising antibody drug conjugates (ADCs) that target BCMA.[French] L'invention concerne des procédés de cartographie peptidique de marquage isotopique stable (SIL) pour une quantification précise et sensible d'un site de conjugaison. L'invention concerne également des compositions comprenant des conjugués anticorps-médicament (ADC) ciblant BCMA.
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