WO2023286016 - SYSTEMS AND METHODS FOR HANDLING AND ANALYZING SAMPLES

National phase entry:
Publication Number WO/2023/286016
Publication Date 19.01.2023
International Application No. PCT/IB2022/056513
International Filing Date 14.07.2022
Title **
[English] SYSTEMS AND METHODS FOR HANDLING AND ANALYZING SAMPLES
[French] SYSTÈMES ET PROCÉDÉS DE MANIPULATION ET D'ANALYSE D'ÉCHANTILLONS
Applicants **
DH TECHNOLOGIES DEVELOPMENT PTE. LTD. 33 Marsiling Industrial Estate Road 3 #04-06 Singapore, SG
Inventors
COVEY, Thomas R. 71 Four Valley Drive Concord, Ontario L4K 4V8, CA
LIU, Chang 71 Four Valley Drive Concord, Ontario L4K 4V8, CA
Priority Data
63/222,236   15.07.2021   US
63/255,666   14.10.2021   US
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Quotation for National Phase entry

Country StagesTotal
China Filing1441
EPO Filing, Examination6989
Japan Filing591
South Korea Filing607
USA Filing, Examination2910
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Total: 12538

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] Methods and systems for handling and/or analyzing samples are provided. In one example, a method comprises: introducing (406), with a liquid handler (322), at least one assisting agent into a sample well (310) of a well plate (312), wherein the sample comprises a sample volume; and ejecting (408), with an acoustic droplet ejector, ADE, (306), a mixture comprising the sample mixed with the at least one assisting agent from the sample well, wherein the at least one assisting agent interacts (406) with an analyte of the sample to limit gel formation at a top surface of the sample volume, prior to the mixture ejection.[French] L'invention concerne des procédés et des systèmes de manipulation et/ou d'analyse d'échantillons. Dans un exemple, un procédé comprend : l'introduction (406), avec un dispositif de manipulation de liquide (322), d'au moins un agent d'aide dans un puits d'échantillon (310) d'une plaque de puits (312), l'échantillon comprenant un volume d'échantillon ; et l'éjection (408), avec un éjecteur de gouttelettes acoustiques, ADE, (306), d'un mélange comprenant l'échantillon mélangé avec le ou les agents d'aide du puits d'échantillon, le ou les agents d'aide interagissant (406) avec un analyte de l'échantillon pour limiter la formation de gel au niveau d'une surface supérieure du volume d'échantillon, avant l'éjection du mélange.
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