WO2022254376 - NEODEGRADER CONJUGATES

National phase entry:
Publication Number WO/2022/254376
Publication Date 08.12.2022
International Application No. PCT/IB2022/055167
International Filing Date 02.06.2022
Title **
[English] NEODEGRADER CONJUGATES
[French] CONJUGUÉS DE NÉO-DÉGRADATEURS
Applicants **
ORUM THERAPEUTICS, INC. 2F, 281-25, Munji-ro Yuseong-gu, Daejeon 34050, KR
BRISTOL-MYERS SQUIBB COMPANY Route 206 & Province Line Road Lawrenceville, New Jersey 08540, US
Inventors
FISHKIN, Nathan Orum Therapeutics, Ipsen Innovation Center/Biolabs 650 East Kendall St. Cambridge, Massachusetts 02142, US
PARK, Peter U. Orum Therapeutics, Ipsen Innovation Center/Biolabs 650 East Kendall St. Cambridge, Massachusetts 02142, US
BAI, Chen Orum Therapeutics, Ipsen Innovation Center/Biolabs 650 East Kendall St. Cambridge, Massachusetts 02142, US
Priority Data
63/202,273   03.06.2021   US
63/282,585   23.11.2021   US
Application details
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Entry into National Phase under
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Quotation for National Phase entry

Country StagesTotal
China Filing2734
EPO Filing, Examination18929
Japan Filing590
South Korea Filing607
USA Filing, Examination12360
MasterCard Visa

Total: 35220

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] The present disclosure provides neoDegraders and neoDegraders conjugated to binding moieties. Also provided are compositions comprising the conjugates. The compounds and compositions are useful for treating a disease or condition, e.g., cancer, in a subject in need thereof.[French] La présente invention concerne des néo-dégradateurs ainsi que des néo-dégradateurs conjugués à des fractions de liaison. L'invention concerne également des compositions comprenant les conjugués. Les composés et les compositions sont utiles pour traiter une maladie ou un état, par exemple, un cancer, chez un sujet en ayant besoin.
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