WO2022215017 - TREATMENTS FOR PRURIGO NODULARIS

National phase entry:
Publication Number WO/2022/215017
Publication Date 13.10.2022
International Application No. PCT/IB2022/053250
International Filing Date 07.04.2022
Title **
[English] TREATMENTS FOR PRURIGO NODULARIS
[French] TRAITEMENTS CONTRE LE PRURIGO NODULAIRE
Applicants **
GALDERMA HOLDING SA
CHUGAI SEIYAKU KABUSHIKI KAISHA
Inventors
JULIA, Valerie
KRISHNASWAMY, Jayendra Kumar
PIKETTY, Christophe
ROUSSEAU, Francois
Priority Data
63/172,020   07.04.2021   US
63/323,409   24.03.2022   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting17621
EPO Filing, Examination, Granting132568
Japan Filing, Examination, Granting5144
South Korea Filing, Examination, Granting8978
USA Filing, Examination, Granting32140
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Total: 196,451

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] Described herein are treatments and preventions for prurigo nodularis (PN), antibodies and pharmaceutical compositions for use in the treatment or prevention of PN, and uses of an anti-IL-31RA antibody (e.g., nemolizumab) in the manufacture of a medicament for the treatment or prevention of PN. Also described herein are biomarkers of PN and methods of altering or improving these biomarkers via treatments with an antibody that binds to IL-31RA (e.g., nemolizumab).[French] L'invention concerne des traitements thérapeutiques et prophylactiques contre le prurigo nodulaire (PN), des anticorps et des compositions pharmaceutiques destinés à être utilisés dans le traitement ou la prévention du PN, et des utilisations d'un anticorps anti-IL-31 RA (par exemple, némolizumab) dans la fabrication d'un médicament pour le traitement ou la prévention du PN. L'invention concerne également des biomarqueurs de PN et des méthodes de modification ou d'amélioration de ces biomarqueurs par l'intermédiaire de traitements avec un anticorps qui se lie à IL-31 RA (par exemple, némolizumab).