WO2023144580 - INDUCTIVE MATRIX FOR FUNCTIONAL OCULAR SURFACE RECONSTRUCTION
National phase entry is expected:
Publication Number
WO/2023/144580
Publication Date
03.08.2023
International Application No.
PCT/IB2022/050694
International Filing Date
27.01.2022
Title **
[English]
INDUCTIVE MATRIX FOR FUNCTIONAL OCULAR SURFACE RECONSTRUCTION
[French]
MATRICE INDUCTIVE POUR LA RECONSTRUCTION DE SURFACE OCULAIRE FONCTIONNELLE
Applicants **
ALVARADO, Carlos A
7 calle 35-64 zona 11, Colonia el Zompopero
Guatemala, 1011, GT
Inventors
ALVARADO, Carlos A
7 calle 35-64 zona 11, Colonia el Zompopero
Guatemala, 1011, GT
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
| * | |
| * | |
International Searching Authority |
SPTO
* |
| Applicant's Legal Status |
Natural Person
* |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Translation |
|
Recalculate
* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing | 374 | |
| EPO | Filing, Examination | 3296 | |
| Japan | Filing | 497 | |
| South Korea | Filing | 450 | |
| USA | Filing, Examination | 1460 |
Total: 6077 USD
The term for entry into the National Phase has expired. This quotation is for informational purposes only
Abstract[English]
A new method is provided that precisely harmonizes the structural and functional biological processes that lead to the optimal reconstruction of ocular surface disorders. The method consists of the administration of a trilaminar (3D) material, which comprises the mucosa, the basement membrane, and the submucosa of the porcine esophagus in a stabilized conformation of integrated layers, which accurately imitates ocular structures, whose mechanical properties, biocompatibility, and integration into the host's tissues, facilitate the structural and functional restoration of lost or damaged ocular tissues. Through the mimesis of the spatial microenvironments generated by their structure and their functional conjugation with the signals of the host's extracellular matrix, the reconstruction of the neo-tissue is successfully guided..[French]
La présente invention concerne une nouvelle méthode qui permet d'harmoniser avec précision les processus biologiques structurels et fonctionnels qui conduisent à une reconstruction optimale des troubles de la surface oculaire. La méthode consiste à administrer un matériau trilaminaire (3D), qui comprend la muqueuse, la membrane basale et la sous-muqueuse de l'œsophage porcin dans une conformation stabilisée de couches intégrées, qui imite avec précision les structures oculaires, dont les propriétés mécaniques, la biocompatibilité et l'intégration dans les tissus de l'hôte facilitent la restauration structurelle et fonctionnelle des tissus oculaires perdus ou endommagés. Par l'imitation des micro-environnements spatiaux générés par leur structure et leur conjugaison fonctionnelle avec les signaux de la matrice extracellulaire de l'hôte, la reconstruction du néo-tissu est guidée avec succès.