WO2022153161 - TREATMENT OF CANCER USING A PRMT5 INHIBITOR

National phase entry is expected:
Publication Number WO/2022/153161
Publication Date 21.07.2022
International Application No. PCT/IB2022/050154
International Filing Date 10.01.2022
Title **
[English] TREATMENT OF CANCER USING A PRMT5 INHIBITOR
[French] TRAITEMENT DU CANCER À L'AIDE D'UN INHIBITEUR DE PRMT5
Applicants **
PFIZER INC. 66 Hudson Boulevard East New York, New York 10001-2192, US
Inventors
JENSEN-PERGAKES, Kristen Lee c/o Pfizer Inc. 10777 Science Center Drive San Diego, California 92121, US
WANG, Yuli 4237 Calle Mejillones San Diego, California 92130, US
XIE, Tao c/o Pfizer Inc. 10777 Science Center Drive San Diego, California 92121, US
Priority Data
63/137,410   14.01.2021   US
63/289,106   13.12.2021   US
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Quotation for National Phase entry

Country StagesTotal
China Filing1562
EPO Filing, Examination7024
Japan Filing590
South Korea Filing607
USA Filing, Examination3910
MasterCard Visa

Total: 13693

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] The present disclosure describes methods of treating cancer in a subject having a splicing factor mutation comprising administering to the subject in need thereof a therapeutically effective amount of a S-adenosylmethionine (SAM)-competitive Protein Arginine Methyltransferase 5 (PRMT5) inhibitor.[French] La présente divulgation concerne des procédés de traitement du cancer chez un sujet ayant une mutation de facteur d'épissage, comprenant l'administration au sujet en ayant besoin d'une quantité thérapeutiquement efficace d'un inhibiteur de la protéine arginine méthyltransférase 5 (PRMT5) S-adénosylméthionine (SAM)-compétitif.
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