WO2023073429 - METHODS OF USING ANTI-EGF ANTIBODIES TO AUGMENT THE ACTIVITY OF BRAF AND KRAS INHIBITORS

National phase entry:
Publication Number WO/2023/073429
Publication Date 04.05.2023
International Application No. PCT/IB2022/000655
International Filing Date 28.10.2022
Title **
[English] METHODS OF USING ANTI-EGF ANTIBODIES TO AUGMENT THE ACTIVITY OF BRAF AND KRAS INHIBITORS
[French] MÉTHODES D'UTILISATION D'ANTICORPS ANTI-EGF POUR AUGMENTER L'ACTIVITÉ D'INHIBITEURS DE BRAF ET DE KRAS
Applicants **
IN3BIO LTD.
D'HONDT, Erik
MOLINA-VILA, Miguel, Angel
Inventors
D'HONDT, Erik
MOLINA-VILA, Miguel, Angel
Priority Data
63/272,822   28.10.2021   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2210
EPO Filing, Examination, Granting9687
Japan Filing, Examination, Granting2243
South Korea Filing, Examination, Granting2139
USA Filing, Examination, Granting5940
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Total: 22,219

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Abstract[English] Embodiments of the present disclosure are directed to methods for treating and preventing disease conditions, such as cancer, particularly in those individuals who have developed a resistance to, or who are not responsive to, cancer therapies involving v-Raf murine sarcoma viral oncogene homolog B1 (BRAF) or Kirsten rat sarcoma oncogene homolog (KRAS) inhibitors.[French] Des modes de réalisation de la présente divulgation concernent des méthodes de traitement et de prévention d'états pathologiques, tels que le cancer, en particulier chez les individus qui ont développé une résistance à, ou qui ne sont pas sensibles aux cancérothérapies impliquant des inhibiteurs de l'homologue de l'oncogène BI viral du sarcome murin v-Raf (BRAF) ou des inhibiteurs de l'homologue de l'oncogène du sarcome de rat de Kirsten (KRAS).

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