WO2023079362 - PROCESSABLE COMPOSITIONS AND USE FOR THE SAME

National phase entry:
Publication Number WO/2023/079362
Publication Date 11.05.2023
International Application No. PCT/IB2022/000649
International Filing Date 02.11.2022
Title **
[English] PROCESSABLE COMPOSITIONS AND USE FOR THE SAME
[French] COMPOSITIONS APTES À ÊTRE TRAITÉES ET LEUR UTILISATION
Applicants **
RIPPLE THERAPEUTICS CORPORATION Mars Centre, South Tower 101 College Street, Suite 300 Toronto, ON M5G IL7, CA
Inventors
PARRAG, Ian, Charles Mars Centre, South Tower 101 College Street, Suite 300 Toronto, ON M5G IL7, CA
STATHAM, Matthew, Alexander John Mars Centre, South Tower 101 College Street, Suite 300 Toronto, ON M5G IL7, CA
BATTISTON, Kyle, Giovanni Mars Centre, South Tower 101 College Street, Suite 300 Toronto, ON M5G IL7, CA
NAIMARK, Wendy, Alison Mars Centre, South Tower 101 College Street, Suite 300 Toronto, ON M5G IL7, CA
DAY, Jonathan Mars Centre, South Tower 101 College Street, Suite 300 Toronto, ON M5G IL7, CA
BALDWIN, Emily Mars Centre, South Tower 101 College Street, Suite 300 Toronto, ON M5G IL7, CA
Priority Data
63/275,281   03.11.2021   US
63/275,283   03.11.2021   US
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Quotation for National Phase entry

Country StagesTotal
China Filing6769
EPO Filing, Examination107395
Japan Filing587
South Korea Filing606
USA Filing, Examination36560
MasterCard Visa

Total: 151917

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] Provided herein are compounds having the formula D1-L-D2, wherein D1 is a processable group, L is a linker, and D2 is a drug. Also described herein are pharmaceutical compositions comprising said compounds and methods for the treatment of ocular diseases or disorders including glaucoma, ocular hypertension, ocular inflammation, diabetic macular edema, posterior inflammation, anterior inflammation, macular degeneration, post-cataract surgery and retinal vein occlusion.[French] L'invention concerne des composés ayant la formule D1-L-D2, D1 étant un groupe apte à être traité, L un lieur et D2 un médicament. L'invention concerne également des compositions pharmaceutiques comprenant lesdits composés et des procédés pour le traitement de maladies ou de troubles oculaires comprenant le glaucome, l'hypertension oculaire, l'inflammation oculaire, l'œdème maculaire diabétique, l'inflammation postérieure, l'inflammation antérieure, la dégénérescence maculaire, la chirurgie post-cataracte et l'occlusion veineuse rétinienne.
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