WO2023067387 - COMPOUNDS AND METHODS FOR THE TREATMENT OF DERMAL AND OCULAR DISORDERS
National phase entry:
Publication Number
WO/2023/067387
Publication Date
27.04.2023
International Application No.
PCT/IB2022/000609
International Filing Date
19.10.2022
Title **
[English]
COMPOUNDS AND METHODS FOR THE TREATMENT OF DERMAL AND OCULAR DISORDERS
[French]
COMPOSÉS ET MÉTHODES POUR LE TRAITEMENT DE TROUBLES DERMIQUES ET OCULAIRES
Applicants **
AZURA OPHTHALMICS LTD.
5 Druyanov Street
6314305 Tel Aviv, IL
Inventors
HOLMES, Ian
Levlel 9, 31 Queen Street
Melbourne, Vic, 3000, AU
ALSTER, Yair
5 Druyanov Street
6314305 Tel Aviv, IL
BARASH, Hila
5 Druyanov Street
6314305 Tel Aviv, IL
BOSWORTH, Charles
5 Druyanov Street
6314305 Tel Aviv, IL
RAFAELI, Omer
5 Druyanov Street
6314305 Tel Aviv, IL
BURK, Robert, M.
5 Druyanov Street
6314305 Tel Aviv, IL
GLEESON, Marc
Level 9, 31 Queen Street
Melbourne, Vic, 3000, AU
STEWART, Mark, Richard
Chesterford Research Park
Saffron Walden, Essex CB10 1XL, GB
DUNN, Jonathan
Chesterford Research Park
Saffron Walden, Essex CB10 1XL, GB
KATSINA, Soultana
Chesterford Research Park
Saffron Walden, Essex CB10 1XL, GB
PILEGGI, Elisa
Chesterford Research Park
Saffron Walden, Essex CB10 1XL, GB
NICHOLLS, Alexander, James
Chesterford Research Park
Saffron Walden, Essex CB10 1XL, GB
Priority Data
63/257,855
20.10.2021
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
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International Searching Authority |
USPTO
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Translation |
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Recalculate
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing | 4690 | |
| EPO | Filing, Examination | 69318 | |
| Japan | Filing | 588 | |
| South Korea | Filing | 574 | |
| USA | Filing, Examination | 25580 |
Total: 100750 USD
The term for entry into the National Phase has expired. This quotation is for informational purposes only
Abstract[English]
Described herein are compositions and methods for the treatment or prevention of dermal or ocular surface disorders. Ocular surface disorders include ocular allergy, dry eye disease, ocular manifestation of graft versus host disease and other inflammatory and/or infectious diseases of the (e.g., anterior) surface of the eye(s). Said compositions and methods comprise keratolytic conjugates which demonstrate immunological, keratolytic, anti-inflammatory, and/or other desirable activities. Topical administration of said compositions to the eyelid margin or surrounding areas provides therapeutic benefit to patients suffering from ocular surface disorders.[French]
L'invention concerne des compositions et des méthodes pour le traitement ou la prévention de troubles de la surface dermique ou oculaire. Les troubles de la surface oculaire comprennent l'allergie oculaire, la maladie de l'oeil sec, une manifestation oculaire de la maladie du greffon contre l'hôte et d'autres maladies inflammatoires et/ou infectieuses de la surface (par exemple, antérieure) de l'oeil/des yeux. Lesdites compositions et méthodes comprennent des conjugués kératolytiques qui présentent des activités immunologiques, kératolytiques, anti-inflammatoires et/ou d'autres activités souhaitées. L'administration topique desdites compositions à la marge des paupières ou au niveau de zones environnantes procure un bénéfice thérapeutique à des patients atteints de troubles de la surface oculaire.