WO2022070047 - METHOD AND APPARATUS FOR DELIVERING TUMOR TREATING FIELDS TO A TORSO, AND METHOD FOR DETERMINING LOCATIONS FOR TRANSDUCERS TO DELIVER TUMOR TREATING FIELDS

National phase entry:
Publication Number WO/2022/070047
Publication Date 07.04.2022
International Application No. PCT/IB2021/058877
International Filing Date 29.09.2021
Title **
[English] METHOD AND APPARATUS FOR DELIVERING TUMOR TREATING FIELDS TO A TORSO, AND METHOD FOR DETERMINING LOCATIONS FOR TRANSDUCERS TO DELIVER TUMOR TREATING FIELDS
[French] PROCÉDÉ ET APPAREIL PERMETTANT D'ADMINISTRER DES CHAMPS DE TRAITEMENT DE TUMEUR À UN TORSE, ET PROCÉDÉ PERMETTANT DE DÉTERMINER DES EMPLACEMENTS POUR DES TRANSDUCTEURS DESTINÉS À DÉLIVRER DES CHAMPS DE TRAITEMENT DE TUMEUR
Applicants **
NOVOCURE GMBH Park 6 CH-6039 Root D4, CH
Inventors
FARBER, Ori c/o Novocure GmbH, Topaz Building, 4th Floor MATAM Center, PO Box 15022, Sha'ar HaCarmel 15022 Haifa, IL
NAVEH, Ariel c/o Novocure GmbH, Topaz Building, 4th Floor MATAM Center, PO Box 15022, Sha'ar HaCarmel 15022 Haifa, IL
WASSERMAN, Yoram c/o Novocure GmbH, Topaz Building, 4th Floor MATAM Center, PO Box 15022, Sha'ar HaCarmel 31905 Haifa, IL
Priority Data
63/085,934   30.09.2020   US
17/487,432   28.09.2021   US
63/181,031   28.04.2021   US
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Quotation for National Phase entry

Country StagesTotal
China Filing1308
EPO Filing, Examination4722
Japan Filing591
South Korea Filing640
USA Filing, Examination2710
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Total: 9971

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] A method of applying tumor treating fields to a torso of a subject's body, the method including: locating a first transducer at a first location of the subject's body, the first location being on the torso of the subject's body; locating a second transducer at a second location of the subject's body, the second location being below the torso of the subject's body; and inducing an electric field between at least part of the first transducer and at least part of the second transducer. Also provided is a system to apply tumor treating fields to a torso of a subject's body, the system comprising: a first transducer adapted to be located at a first location of the subject's body, the first location being on the torso of the subject's body; a second transducer adapted to be located at a second location of the subject's body, the second location being below the torso of the subject's body; a voltage generator adapted to be coupled to the first transducer and the second transducer and capable of providing first voltage to the first transducer and second voltage to the second transducer; and a controller coupled to the voltage generator, the controller comprising one or more processors and memory accessible by the one or more processors, the memory storing instructions that when executed by the one or more processors, cause the controller to instruct the voltage generator to generate the first voltage and the second voltage to induce an electric field in the torso of the subject's body, the electric field having field intensities of at least 1.0 V/cm in at least 50% of volume of the torso of the subject's body. A computer- implemented method to determine placement of transducers on a subject's body for inducing tumor treating fields, the computer comprising one or more processors and memory accessible by the one or more processors, the memory storing instructions that when executed by the one or more processors cause the computer to perform the method, the method comprising: selecting a plurality of pairs of locations on the subject's body, each pair of locations having a first location to locate a first transducer and a second location to locate a second transducer; obtaining a model of AC electrical conductivity in a portion of the subject's body; obtaining, for each location in the plurality of pairs of locations on the subject's body, an indication of heat removal potential at a surface of the subject's body; selecting one or more recommended pairs of first locations and second locations based at least on the model of AC electrical conductivity and the indication of heat removal potential for each location; and outputting the one or more recommended pairs of first locations and second locations.[French] L'invention concerne un procédé d'application de champs de traitement de tumeur au torse du corps d'un sujet, le procédé comprenant : la localisation d'un premier transducteur à un premier emplacement du corps du sujet, le premier emplacement étant sur le torse du corps du sujet ; la localisation d'un second transducteur à un second emplacement du corps du sujet, le second emplacement étant au-dessous du torse du corps du sujet ; et l'induction d'un champ électrique entre au moins une partie du premier transducteur et au moins une partie du second transducteur.
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