WO2024194663 - PROCESS FOR THE PREPARATION OF UPADACITINIB ACTIVE SUBSTANCE AND INTERMEDIATES
National phase entry:
Publication Number
WO/2024/194663
Publication Date
26.09.2024
International Application No.
PCT/HU2024/050020
International Filing Date
22.03.2024
Title **
[English]
PROCESS FOR THE PREPARATION OF UPADACITINIB ACTIVE SUBSTANCE AND INTERMEDIATES
[French]
PROCÉDÉ DE PRÉPARATION D'UNE SUBSTANCE ACTIVE D'UPADACITINIB ET INTERMÉDIAIRES
Applicants **
EGIS GYÓGYSZERGYÁR ZRT.
Keresztúri út 30-38.
1106 Budapest, HU
Inventors
MÁNDI, Géza
Rózsa u. 46. 2A
1064 Budapest, HU
NAGY, Tamás
Hunyad lejtő 28/2
1121 Budapest, HU
KURUNCZI, Erika
Drégelyvár utca 21 4/23
1158 Budapest, HU
ABONYI, Attila László
Aranylúd utca 4
1173 Budapest, HU
PORCS-MAKKAY, Márta
Hunyadi János utca 22B 1a
1188 Budapest, HU
Priority Data
P2300099
23.03.2023
HU
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
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International Searching Authority |
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| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
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| Translation |
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Recalculate
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing | 1072 | |
| EPO | Filing, Examination | 6549 | |
| Japan | Filing | 531 | |
| South Korea | Filing | 575 | |
| USA | Filing, Examination | 5225 |
Total: 13952 USD
The term for entry into the National Phase has expired. This quotation is for informational purposes only
Abstract[English]
The object of the invention is the preparation of upadacitinib drug substance of the formula (I) by a new process, which is novel, environmentally friendly, has an advantageous pollution profile, and also can be realized on an industrial scale, using novel intermediates not yet known from the literature.[French]
L'invention a pour objet la préparation d'une substance médicamenteuse d'upadacitinib de formule (I) selon un nouveau procédé, qui est nouveau, respectueux de l'environnement, a un profil de pollution avantageux, et peut également être mis en oeuvre à l'échelle industrielle, à l'aide de nouveaux intermédiaires non encore connus de la littérature.