WO2024194662 - PROCESS FOR THE PREPARATION OF UPADACITINIB
National phase entry:
Publication Number
WO/2024/194662
Publication Date
26.09.2024
International Application No.
PCT/HU2024/050019
International Filing Date
22.03.2024
Title **
[English]
PROCESS FOR THE PREPARATION OF UPADACITINIB
[French]
PROCÉDÉ DE PRÉPARATION D'UPADACITINIB
Applicants **
EGIS GYÓGYSZERGYÁR ZRT.
Inventors
MÁNDI, Géza
NAGY, Tamás
PORCS-MAKKAY, Márta
ABONYI, Attila László
KURUNCZI, Erika
Priority Data
P2300098
23.03.2023
HU
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
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International Searching Authority |
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2180 | |
| EPO | Filing, Examination, Granting | 11950 | |
| Japan | Filing, Examination, Granting | 2243 | |
| South Korea | Filing, Examination, Granting | 2019 | |
| USA | Filing, Examination, Granting | 5530 |

Total:
23,922
The term for entry into the National Phase has expired. This quotation is for informational purposes only
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Abstract[English]
The object of the invention is the preparation of upadacitinib drug substance of the formula (I) by a new process, which is novel, environmentally friendly, has an advantageous pollution profile, and also can be realized on an industrial scale, using novel intermediates not yet known from the literature.[French]
L'objet de l'invention est la préparation d'une substance médicamenteuse, l'upadacitinib, de formule (I) au moyen d'un nouveau procédé, qui est nouveau, respectueux de l'environnement, a un profil de pollution avantageux, et peut également être mis en oeuvre à l'échelle industrielle, à l'aide de nouveaux intermédiaires non encore connus de la littérature.