WO2023118820 - CANCER SPECIFIC T-CELL RECEPTORS

National phase entry is expected:
Publication Number WO/2023/118820
Publication Date 29.06.2023
International Application No. PCT/GB2022/053273
International Filing Date 16.12.2022
Title **
[English] CANCER SPECIFIC T-CELL RECEPTORS
[French] RÉCEPTEURS DE LYMPHOCYTES T SPÉCIFIQUES DU CANCER
Applicants **
CONTINUUM LIFE SCIENCES LIMITED 2nd Floor, Berkeley Square House Berkeley Square London W1J 6BD, GB
Inventors
SEWELL, Andrew Cardiff University School of Medicine Henry Wellcome Building, Heath Park Cardiff CF14 4XN, GB
RIUS, Cristina Cardiff University School of Medicine Henry Wellcome Building, Heath Park Cardiff CF14 4XN, GB
DOLTON, Gary Cardiff University School of Medicine Henry Wellcome Building, Heath Park Cardiff CF14 4XN, GB
WOOLLEY, Rachel Monarch House, 7 Barton Lane Abingdon Science Park Abingdon OX14 3NB, GB
Priority Data
2118699.4   21.12.2021   GB
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Quotation for National Phase entry

Country StagesTotal
China Filing1304
EPO Filing, Examination6240
Japan Filing589
South Korea Filing575
USA Filing, Examination3910
MasterCard Visa

Total: 12618

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] The present invention provides novel T cell receptor (TCR) based molecules which are selective for IMP2. The TCR of the invention are of use for the diagnosis, treatment and prevention of IMP2 expressing cancerous diseases. Further provided are nucleic acids encoding the TCR of the invention, vectors comprising these nucleic acids, recombinant cells expressing the TCR and pharmaceutical compositions comprising the compounds of the invention.[French] La présente invention concerne de nouvelles molécules à base de récepteurs de lymphocytes T (TCR) qui sont sélectives pour IMP2. Le TCR de l'invention est utile pour le diagnostic, le traitement et la prévention de maladies cancéreuses exprimant IMP2. L'invention concerne en outre des acides nucléiques codant pour le TCR de l'invention, des vecteurs comprenant ces acides nucléiques, des cellules recombinantes exprimant le TCR et des compositions pharmaceutiques comprenant les composés de l'invention.
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