WO2026114983 - THERAPEUTIC COMBINATION COMPRISING N-{3-[4-AMINO-7-(1-METHYL-PIPERIDIN-4-YL)-7H-PYRROLO[2,3-D]PYRIMIDIN-5-YL]-2-FLUORO-PHENYL}-5-CHLORO-2-FLUORO-4-METHOXY-BENZENE SULFONAMIDE COMPOUND AND ANTINEOPLASTIC AGENTS

National phase entry is expected:
Publication Number WO/2026/114983
Publication Date 04.06.2026
International Application No. PCT/EP2025/084419
International Filing Date 26.11.2025
Title **
[English] THERAPEUTIC COMBINATION COMPRISING N-{3-[4-AMINO-7-(1-METHYL-PIPERIDIN-4-YL)-7H-PYRROLO[2,3-D]PYRIMIDIN-5-YL]-2-FLUORO-PHENYL}-5-CHLORO-2-FLUORO-4-METHOXY-BENZENE SULFONAMIDE COMPOUND AND ANTINEOPLASTIC AGENTS
[French] COMBINAISON THÉRAPEUTIQUE COMPRENANT LE COMPOSÉ N-{3-[4-AMINO-7-(1-MÉTHYL-PIPÉRIDIN-4-YL)-7H-PYRROLO[2,3-D]PYRIMIDIN-5-YL]-2-FLUORO-PHÉNYL}-5-CHLORO-2-FLUORO-4-MÉTHOXY-BENZÈNE SULFONAMIDE ET DES AGENTS ANTINÉOPLASIQUES
Applicants **
NERVIANO MEDICAL SCIENCES S.R.L.
Inventors
PERRERA, Claudia
MAHNKE, Lisa
CARENZI, Davide
LOMBARDI BORGIA, Andrea
Priority Data
24216599.1   29.11.2024   EP
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2662
EPO Filing, Examination, Granting13710
Japan Filing, Examination, Granting2400
South Korea Filing, Examination, Granting2568
USA Filing, Examination, Granting7140
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Total: 28,480
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Abstract[English] The present invention relates to combinations comprising N-{3-[4-Amino-7-(1-methyl-piperidin-4-yl)-7H-pyrrolo[2,3- d]pyrimidin-5-yl]-2-fluoro-phenyl}-5-chloro-2-fluoro-4-methoxy-benzenesulfonamide or its pharmaceutically acceptable salt and antineoplastic agents. The invention also relates to the use of said combination in the treatment of cancer.[French] La présente invention concerne des combinaisons comprenant le N-{3-[4-amino-7-(1-méthyl-pipéridin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-fluoro-phényl}-5-chloro-2-fluoro-4-méthoxy-benzènesulfonamide ou son sel pharmaceutiquement acceptable et des agents antinéoplasiques. L'invention concerne également l'utilisation de ladite combinaison dans le traitement du cancer.