WO2026062178 - GENETIC RISK FACTORS FOR ATYPICAL FRONTOTEMPORAL LOBAR DEGENERATION WITH UBIQUITIN INCLUSIONS
National phase entry is expected:
Publication Number
WO/2026/062178
Publication Date
26.03.2026
International Application No.
PCT/EP2025/076785
International Filing Date
19.09.2025
Title **
[English]
GENETIC RISK FACTORS FOR ATYPICAL FRONTOTEMPORAL LOBAR DEGENERATION WITH UBIQUITIN INCLUSIONS
[French]
FACTEURS DE RISQUE GÉNÉTIQUE POUR LA DÉGÉNÉRESCENCE LOBAIRE FRONTOTEMPORALE ATYPIQUE AVEC DES INCLUSIONS D'UBIQUITINE
Applicants **
VIB VZW
UNIVERSITEIT ANTWERPEN
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
Inventors
RADEMAKERS, Rosa
DE COSTER, Wouter
Priority Data
63/696,468
19.09.2024
US
Application details
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International Searching Authority |
EPO
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2279 | |
| EPO | Filing, Examination, Granting | 9354 | |
| Japan | Filing, Examination, Granting | 2093 | |
| South Korea | Filing, Examination, Granting | 1945 | |
| USA | Filing, Examination, Granting | 5340 |
Total:
21,011
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Abstract[English]
The invention relates to genetic risk factors that are associated with frontotemporal lobar degeneration (FTLD), in particular with atypical FTLD with ubiquitin inclusions (aFTLD-U). These genetic risk factors are located on the chr15q14 locus and are detectable beyond the brain, thus opening avenues for more precise ante-mortem identification of this type of FTLD patients.[French]
L'invention concerne des facteurs de risque génétique qui sont associés à la dégénérescence lobaire frontotemporale (FTLD), en particulier à la FTLD atypique avec des inclusions d'ubiquitine (aFTLD-U). Ces facteurs de risque génétique sont situés sur le locus chr15q14 et sont détectables au-delà du cerveau, ouvrant ainsi des voies pour une identification ante-mortem plus précise de ce type de patients FTLD.