WO2025017212 - UDP-GLUCOSE CERAMIDE GLUCOSYLTRANSFERASE SYNTHASE (UGCG) INHIBITORS IN THE TREATMENT OF CANCER

National phase entry is expected:
Publication Number WO/2025/017212
Publication Date 23.01.2025
International Application No. PCT/EP2024/070717
International Filing Date 22.07.2024
Title **
[English] UDP-GLUCOSE CERAMIDE GLUCOSYLTRANSFERASE SYNTHASE (UGCG) INHIBITORS IN THE TREATMENT OF CANCER
[French] INHIBITEURS DE SYNTHASE DE GLUCOSYLTRANSFÉRASE DE CÉRAMIDE D'UDP-GLUCOSE (UGCG) DANS LE TRAITEMENT DU CANCER
Applicants **
KATHOLIEKE UNIVERSITEIT LEUVEN
Inventors
BELOTSERKOVSKY, Jaroslav
DEHAIRS, Jonas
DE LAAT, Vincent
IDKOWIAK, Jakub
SWINNEN, Johannes
TALEBI, Ali
VANDERHOYDONC, Frank
Priority Data
23186690.6   20.07.2023   EP
23210507.2   17.11.2023   EP
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2731
EPO Filing, Examination, Granting17384
Japan Filing, Examination, Granting2677
South Korea Filing, Examination, Granting3172
USA Filing, Examination, Granting7140
MasterCard Visa
Total: 33,104

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] The invention relates to chemotherapy agents such as gemcitabine and and inhibitors of UDP-glucose ceramide glucosyltransferase synthase (UGCG) such as miglustat, lucerastat, sinbaglustat, eliglustat, ibiglustat, for use in the treatment of cancers, such as pancreatic cancers.[French] L'invention concerne des agents de chimiothérapie tels que la gemcitabine et des inhibiteurs de synthase de glucosyltransférase de céramide d'udp-glucose (UGCG) tels que le miglustat, le lucérastat, le sinbaglustat, l'éliglustat, l'ibiglustat, destinés à être utilisés dans le traitement de cancers, tels que des cancers du pancréas.

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