WO2025012213 - ARTIFICIAL SIGNAL PEPTIDES

National phase entry is expected:
Publication Number WO/2025/012213
Publication Date 16.01.2025
International Application No. PCT/EP2024/069205
International Filing Date 08.07.2024
Title **
[English] ARTIFICIAL SIGNAL PEPTIDES
[French] PEPTIDES SIGNAUX ARTIFICIELS
Applicants **
NOVOZYMES A/S
Inventors
PULTZ, Dennis
MOUILLON, Jean-Marie
HALLIN, Peter Fischer
BRAENDSTRUP, Eik
CHRISTENSEN, Pernille, Hvid
Priority Data
23184446.5   10.07.2023   EP
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting1955
EPO Filing, Examination, Granting8811
Japan Filing, Examination, Granting2056
South Korea Filing, Examination, Granting1779
USA Filing, Examination, Granting7140
MasterCard Visa
Total: 21,741

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] The present invention relates to nucleic acid constructs comprising a first polynucleotide encoding an artificial signal peptide and a second polynucleotide encoding a polypeptide having protease activity; expression vectors and host cells comprising said nucleic acid constructs; methods for producing polypeptides having protease activity; and fusion proteins comprising a protease polypeptide and an artificial signal peptide.[French] La présente invention concerne des constructions d'acides nucléiques comprenant un premier polynucléotide codant pour un peptide signal artificiel et un second polynucléotide codant pour un polypeptide ayant une activité protéase ; des vecteurs d'expression et des cellules hôtes comprenant lesdites constructions d'acides nucléiques ; des procédés de production de polypeptides ayant une activité protéase ; et des protéines de fusion comprenant un polypeptide protéase et un peptide signal artificiel.