WO2025003393 - ENHANCING NEURONAL DIFFERENTIATION OF NEURAL PROGENITOR CELLS
National phase entry is expected:
Publication Number
WO/2025/003393
Publication Date
02.01.2025
International Application No.
PCT/EP2024/068237
International Filing Date
28.06.2024
Title **
[English]
ENHANCING NEURONAL DIFFERENTIATION OF NEURAL PROGENITOR CELLS
[French]
AMÉLIORATION DE LA DIFFÉRENCIATION NEURONALE DE CELLULES PROGÉNITRICES NEURALES
Applicants **
NOVO NORDISK A/S
Novo Alle 1
2880 Bagsværd, DK
Inventors
NICLIS, Jonathan
Novo Alle 1
2880 Bagsværd, DK
DJORDJEVIC, Djordje
Novo Alle 1
2880 Bagsværd, DK
CASTIGLIONI, Veronica
Novo Alle 1
2880 Bagsværd, DK
Priority Data
23182626.4
30.06.2023
EP
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
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| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
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International Searching Authority |
EPO
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
* |
| Translation |
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Recalculate
* The data is based on automatic recognition. Please verify and amend if necessary.
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing | 1612 | |
| EPO | Filing, Examination | 5926 | |
| Japan | Filing | 589 | |
| South Korea | Filing | 575 | |
| USA | Filing, Examination | 2710 |
Total: 11412 USD
The term for entry into the National Phase has expired. This quotation is for informational purposes only
Abstract[English]
The present invention relates to a method for directing differentiation of neural cells into neurons by obtaining a cell population comprising neural cells and contacting the cell population with an inhibitor of NOTCH signaling, wherein the inhibitor of NOTCH signaling is selected from LY411575, Avagacestat, Dibenzazepine, and PF-03084014.[French]
La présente invention concerne un procédé pour diriger la différenciation de cellules neurales en neurones par obtention d'une population de cellules comprenant des cellules neurales et mise en contact de la population de cellules avec un inhibiteur de signalisation NOTCH, l'inhibiteur de signalisation NOTCH étant choisi parmi LY411575, Avagacestat, dibenzazépine et PF-03084014.