WO2024256632 - PHARMACEUTICAL FORMULATIONS OF AN AMYLIN RECEPTOR AGONIST AND A GLP-1 RECEPTOR AGONIST COMPRISING A CYCLODEXTRIN

National phase entry is expected:
Publication Number WO/2024/256632
Publication Date 19.12.2024
International Application No. PCT/EP2024/066541
International Filing Date 14.06.2024
Title **
[English] PHARMACEUTICAL FORMULATIONS OF AN AMYLIN RECEPTOR AGONIST AND A GLP-1 RECEPTOR AGONIST COMPRISING A CYCLODEXTRIN
[French] FORMULATIONS PHARMACEUTIQUES UN AGONISTE DU RÉCEPTEUR DE L'AMYLINE ET UN AGONISTE DU RÉCEPTEUR GLP-1 COMPRENANT UNE CYCLODEXTRINE
Applicants **
NOVO NORDISK A/S Novo Alle 1 2880 Bagsværd, DK
Inventors
KJELDSEN, Benjamin, Troest Novo Alle 1 2880 Bagsværd, DK
HANSEN, Rosa, Rebecca, Erritzøe Novo Alle 1 2880 Bagsværd, DK
CHRISTOFFERSEN, Stig Novo Alle 1 2880 Bagsværd, DK
Priority Data
23179381.1   15.06.2023   EP
23180629.0   21.06.2023   EP
Application details
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Quotation for National Phase entry

Country StagesTotal
China Filing1776
EPO Filing, Examination6729
Japan Filing533
South Korea Filing607
USA Filing, Examination3685
MasterCard Visa

Total: 13330

Abstract[English] Disclosed herein is a preserved liquid pharmaceutical formulation comprising an amylin receptor agonist, a GLP-1 receptor agonist, a cyclodextrin comprising hydroxypropyl substitutions and one or more preservatives. Said co-formulation may be used for the medical treatment of subjects with overweight or obesity, with or without associated co-morbidities; diabetes, with or without associated comorbidities; and cardiovascular diseases.[French] L'invention divulgue une formulation pharmaceutique liquide préservée comprenant un agoniste du récepteur de l'amyline, un agoniste du récepteur GLP-1, une cyclodextrine comprenant des substitutions d'hydroxypropyle et un ou plusieurs conservateurs. Ladite coformulation peut être utilisée pour le traitement médical de sujets atteints de surpoids ou d'obésité, avec ou sans comorbidités associées; le diabète, avec ou sans comorbidités associées; et des maladies cardiovasculaires.
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