WO2024200555 - MANUFACTURING METHOD WITH FEEDBACK CONTROL

National phase entry is expected:
Publication Number WO/2024/200555
Publication Date 03.10.2024
International Application No. PCT/EP2024/058325
International Filing Date 27.03.2024
Title **
[English] MANUFACTURING METHOD WITH FEEDBACK CONTROL
[French] PROCÉDÉ DE FABRICATION AVEC COMMANDE DE RÉTROACTION
Applicants **
CHR. HANSEN A/S Boege Alle 10-12 2970 Hoersholm, DK
Inventors
HELLMUTH, Karsten c/o Chr. Hansen GmbH Große Drakenburger Straße 93-97 31582 Nienburg/Weser, DE
BARTLING, Bastian c/o Chr. Hansen GmbH Große Drakenburger Straße 93-97 31582 Nienburg/Weser, DE
GRUENERT, Philipp Paul c/o Chr. Hansen GmbH Große Drakenburger Straße 93-97 31582 Nienburg/Weser, DE
Priority Data
23165791.7   31.03.2023   EP
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Quotation for National Phase entry

Country StagesTotal
China Filing933
EPO Filing, Examination4624
Japan Filing531
South Korea Filing575
USA Filing, Examination2635
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Total: 9298

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] The present disclosure generally relates to a method of manufacturing biological product using fermentation and subsequent purification of the biological product, such as an enzyme. By utilization of online biomass data for a feedback control in the fermenter, an efficient and stable cross-flow microfiltration operation can be performed with active cells.[French] La présente divulgation concerne de manière générale un procédé de fabrication d'un produit biologique par utilisation de la fermentation et purification ultérieure du produit biologique, tel qu'une enzyme. En utilisant les données en ligne sur la biomasse pour un mécanisme de régulation en retour dans le fermenteur, il est possible de réaliser une opération de microfiltration à flux croisé efficace et stable avec des cellules actives.
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