WO2024180207 - PYRIDAZINYL AMINO DERIVATIVES AS ALK5 INHIBITORS

National phase entry is expected:
Publication Number WO/2024/180207
Publication Date 06.09.2024
International Application No. PCT/EP2024/055318
International Filing Date 01.03.2024
Title **
[English] PYRIDAZINYL AMINO DERIVATIVES AS ALK5 INHIBITORS
[French] DÉRIVÉS DE PYRIDAZINYL AMINO UTILISÉS EN TANT QU'INHIBITEURS D'ALK 5
Applicants **
CHIESI FARMACEUTICI S.P.A. Via Palermo 26/A 43122 Parma, IT
Inventors
PIZZIRANI, Daniela c/o Chiesi Farmaceutici S.p.A. Via Palermo 26/A 43122 Parma, IT
RONCHI, Paolo c/o Chiesi Farmaceutici S.p.A. Via Palermo 26/A 43122 Parma, IT
TARSI, Luca c/o Chiesi Farmaceutici S.p.A. Via Palermo 26/A 43122 Parma, IT
Priority Data
23159709.7   02.03.2023   EP
Application details
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Quotation for National Phase entry

Country StagesTotal
China Filing967
EPO Filing, Examination4727
Japan Filing531
South Korea Filing575
USA Filing, Examination2635
MasterCard Visa

Total: 9435

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] The present invention generally relates to compounds inhibiting the transforming growth factor β (TGF β) type I receptor (ALK5) (hereinafter ALK5 inhibitors), methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof; the compounds of the invention may be useful for instance in the treatment of many diseases, disorders, or conditions associated with ALK5 signaling pathway.[French] La présente invention concerne de manière générale des composés inhibant le récepteur du facteur de croissance transformant β (TGFβ) de type I (ALK5) (ci-après, inhibiteurs d'ALK5), des procédés de préparation de tels composés, des compositions pharmaceutiques les contenant et leur utilisation thérapeutique ; les composés de l'invention peuvent être utiles par exemple dans le traitement de maladies, troubles ou états nombreux associés à la voie de signalisation ALK5.
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