WO2024156888 - CD163-BINDING CONJUGATES

National phase entry is expected:
Publication Number WO/2024/156888
Publication Date 02.08.2024
International Application No. PCT/EP2024/051945
International Filing Date 26.01.2024
Title **
[English] CD163-BINDING CONJUGATES
[French] CONJUGUÉS DE LIAISON À CD163
Applicants **
VIB VZW
VRIJE UNIVERSITEIT BRUSSEL
Inventors
VAN GINDERACHTER, Jo
RAES, Geert
VINCKE, Cécile
DEVOOGDT, Nick
DE GROOF, Timo
LAUWERS, Yoline
Priority Data
23153695.4   27.01.2023   EP
23153700.2   27.01.2023   EP
23193741.8   28.08.2023   EP
23193745.9   28.08.2023   EP
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2312
EPO Filing, Examination, Granting8623
Japan Filing, Examination, Granting2183
South Korea Filing, Examination, Granting2116
USA Filing, Examination, Granting6540
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Total: 21,774

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] The invention relates to polypeptides, in particular polypeptides comprising an immunoglobulin domain, binding to human and murine CD163 protein and to applications of such polypeptides such as for use as diagnostic agent, for example as an immunotracer. The invention further relates to conjugates, in particular conjugates of polypeptides comprising an immunoglobulin domain binding to human and murine CD163 protein and a further moiety, such as a therapeutic moiety, and to applications of such conjugates.[French] L'invention concerne des polypeptides, en particulier des polypeptides comprenant un domaine d'immunoglobuline, se liant à la protéine CD163 humaine et murine et des applications de tels polypeptides, telles que pour une utilisation en tant qu'agent de diagnostic, par exemple en tant qu'immunotraceur. L'invention concerne en outre des conjugués, en particulier des conjugués de polypeptides comprenant un domaine d'immunoglobuline se liant à la protéine CD163 humaine et murine et une autre fraction, telle qu'une fraction thérapeutique, et des applications de tels conjugués.

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