WO2023209103 - PREVENTION AND TREATMENT OF INFECTIONS WITH INTRACELLULAR BACTERIA

National phase entry:
Publication Number WO/2023/209103
Publication Date 02.11.2023
International Application No. PCT/EP2023/061133
International Filing Date 27.04.2023
Title **
[English] PREVENTION AND TREATMENT OF INFECTIONS WITH INTRACELLULAR BACTERIA
[French] PRÉVENTION ET TRAITEMENT D'INFECTIONS PAR DES BACTÉRIES INTRACELLULAIRES
Applicants **
UNIVERSITEIT GENT Sint-Pietersnieuwstraat 25 9000 Gent, BE
VIB VZW Rijvisschestraat 120 9052 Zwijnaarde, BE
Inventors
VERBEKE, Rein Faculteit Farmaceutische Wetenschappen Ottergemsesteenweg 460 9000 Gent, BE
LENTACKER, Ine Faculteit Farmaceutische Wetenschappen Ottergemsesteenweg 460 9000 Gent, BE
AERNOUT, Ilke Faculteit Farmaceutische Wetenschappen Ottergemsesteenweg 460 9000 Gent, BE
DE SMEDT, Stefaan Faculteit Farmaceutische Wetenschappen Ottergemsesteenweg 460 9000 Gent, BE
Priority Data
22170792.0   29.04.2022   EP
Application details
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Quotation for National Phase entry

Country StagesTotal
China Filing1223
EPO Filing, Examination4974
Japan Filing591
South Korea Filing575
USA Filing, Examination2710
MasterCard Visa

Total: 10073

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] The present invention relates to a method and composition for prevention and treatment of infections in a subject, in particular with intracellular bacteria. The invention provides an optimized intracellular delivery of an active agent, in particular a nucleic acid, using a nanoparticle formulation including an iNKT cell agonist.[French] La présente invention concerne un procédé et une composition pour la prévention et le traitement d'infections chez un sujet, en particulier par des bactéries intracellulaires. L'invention concerne une administration intracellulaire optimisée d'un agent actif, en particulier d'un acide nucléique, à l'aide d'une formulation de nanoparticules comprenant un agoniste de cellule iNKT.
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