WO2023144275 - ACTUATION OF ORGANOIDS BY MAGNETIC NANOPARTICLES

National phase entry is expected:
Publication Number WO/2023/144275
Publication Date 03.08.2023
International Application No. PCT/EP2023/051942
International Filing Date 26.01.2023
Title **
[English] ACTUATION OF ORGANOIDS BY MAGNETIC NANOPARTICLES
[French] ACTIONNEMENT D'ORGANOÏDES PAR DES NANOPARTICULES MAGNÉTIQUES
Applicants **
KATHOLIEKE UNIVERSITEIT LEUVEN KU Leuven R & D Waaistraat 6 - box 5105 3000 Leuven, BE
Inventors
ABDEL FATTAH, Abdel Rahman Hernstorferstrasse 8-10 1140 Vienna, AT
RANGA, Adrian Avenue du General de Gaulle 20 1050 Ixelles, BE
Priority Data
22153838.2   28.01.2022   EP
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Quotation for National Phase entry

Country StagesTotal
China Filing1122
EPO Filing, Examination4914
Japan Filing590
South Korea Filing574
USA Filing, Examination2710
MasterCard Visa

Total: 9910

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] The invention relates to methods of generating a 3D cellular construct with embedded magnetic nanopartide dusters comprising the steps of: - a) providing a first population of cells labelled with magnetic particles and concentrating the cells into a first duster of cells, - b) adding to the duster of cells obtained in a) a second population of cells which are not labelled with magnetic particles, - c) concentrating said second population of cells into a second duster of cells, - d) cultivating the clusters of cell populations obtained in c) in the presence of an applied magnetic field.[French] L'invention concerne des procédés de génération d'une construction cellulaire 3D avec des dépoussiéreurs de nanoparticules magnétiques incorporés, comprenant les étapes suivantes : - a) mise à disposition d'une première population de cellules marquées par des particules magnétiques et concentration des cellules dans une première poussière de cellules, - b) ajout à la poussière de cellules obtenue en a) d'une seconde population de cellules qui ne sont pas marquées par des particules magnétiques, - c) concentration de ladite seconde population de cellules dans une seconde poussière de cellules, - d) culture des amas de populations de cellules obtenus en c) en présence d'un champ magnétique appliqué.
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