WO2023118050 - USE OF NOVEL MARKERS TO DETECT PLURIPOTENT STEM CELLS

National phase entry is expected:
Publication Number WO/2023/118050
Publication Date 29.06.2023
International Application No. PCT/EP2022/086855
International Filing Date 20.12.2022
Title **
[English] USE OF NOVEL MARKERS TO DETECT PLURIPOTENT STEM CELLS
[French] UTILISATION DE NOUVEAUX MARQUEURS POUR DÉTECTER DES CELLULES SOUCHES PLURIPOTENTES
Applicants **
NOVO NORDISK A/S Novo Allé 2880 Bagsværd, DK
Inventors
NICLIS, Jonathan Novo Alle 1 2880 Bagsværd, DK
CHRISTIANSEN, Josefine, Rågård Novo Alle 1 2880 Bagsværd, DK
ROSKE, Fabian, Vinzenz Novo Alle 1 2880 Bagsværd, DK
EFSTATHOPOULOS, Paschalis Novo Alle 1 2880 Bagsværd, DK
WILLENBROCK, Hanni Novo Alle 1 2880 Bagsværd, DK
Priority Data
21216453.7   21.12.2021   EP
22172461.0   10.05.2022   EP
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Application details
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Quotation for National Phase entry

Country StagesTotal
China Filing1438
EPO Filing, Examination5560
Japan Filing587
South Korea Filing606
USA Filing, Examination2710
MasterCard Visa

Total: 10901

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] The present invention relates to a method of screening a cell population for undifferentiated stem cells by detecting the expression of one or more markers in the cell population, which expression is effectively downregulated as PSCs are differentiated into specialized cells of either of the three germ layers.[French] La présente invention concerne un procédé de criblage d'une population cellulaire à la recherche de cellules souches indifférenciées en détectant l'expression d'un ou plusieurs marqueurs dans la population cellulaire, dont l'expression est effectivement réduite au fur et à mesure que les CSP se différencient en cellules spécialisées de l'une ou l'autre des trois couches germinales.
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