WO2023078868 - CRYSTALLINE FORMS OF A MONOACYLGLYCEROL LIPASE INHIBITOR

National phase entry:
Publication Number WO/2023/078868
Publication Date 11.05.2023
International Application No. PCT/EP2022/080434
International Filing Date 01.11.2022
Title **
[English] CRYSTALLINE FORMS OF A MONOACYLGLYCEROL LIPASE INHIBITOR
[French] FORMES CRISTALLINES D'UN INHIBITEUR DE MONOACYLGLYCÉROL LIPASE
Applicants **
H. LUNDBECK A/S 9, Ottiliavej 2500 Valby, DK
Inventors
ANDREW, Samuel George c/o H. Lundbeck 9, Ottiliavej 2500 Valby, DK
CINCOTTI, Antonio c/o H. Lundbeck A/S 9, Ottiliavej 2500 Valby, DK
PATTERSON, Adam Ross c/o H. Lundbeck 9, Ottiliavej 2500 Valby, DK
EDWARDS, Richard James c/o H. Lundbeck A/S 9, Ottiliavej 2500 Valby, DK
VETTER, Thomas c/o H. Lundbeck A/S 9, Ottiliavej 2500 Valby, DK
JUHL, Martin c/o H. Lundbeck A/S 9, Ottiliavej 2500 Valby, DK
LOPEZ DE DIEGO, Heidi c/o H. Lundbeck A/S 9, Ottiliavej 2500 Valby, DK
GRICE, Cheryl A. c/o H. Lundbeck A/S 2500 Valby, DK
WIENER, John J.M. c/o H. Lundbeck A/S 9, Ottiliavej 2500 Valby, DK
BUZARD, Daniel J. c/o H. Lundbeck A/S 9, Ottiliavej 2500 Valby, DK
ALLAN, Amy c/o H. Lundbeck A/S 9, Ottiliavej 2500 Valby, DK
GANCEDO, Susana Del Rio c/o H. Lundbeck A/S 2500 Valby, DK
Priority Data
63/274,887   02.11.2021   US
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Quotation for National Phase entry

Country StagesTotal
China Filing1393
EPO Filing, Examination5632
Japan Filing595
South Korea Filing575
USA Filing, Examination5110
MasterCard Visa

Total: 13305

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] Described herein is new crystalline forms of the MAGL inhibitor 1-(1-(2-(pyrrolidin-1-yl)-4-(trifluoromethyl)benzyl)-1,8-diazaspiro[4.5]decane-8-carbonyl)-1H-pyrazole-3-carboxylic acid, or a pharmaceutically acceptable salt thereof.[French] L'invention concerne de nouvelles formes cristallines de l'inhibiteur de MAGL 1-(1-(2-(pyrrolidin-1-yl)-4-(trifluorométhyl)benzyl)-1,8-diazaspiro[4,5]décane-8-carbonyl)-1H-pyrazole-3-carboxylique, ou d'un sel pharmaceutiquement acceptable de celui-ci.
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