WO2023066834 - PYRROLIDINE DERIVATIVES AS DDRS INHIBITORS
National phase entry:
Publication Number
WO/2023/066834
Publication Date
27.04.2023
International Application No.
PCT/EP2022/078767
International Filing Date
17.10.2022
Title **
[English]
PYRROLIDINE DERIVATIVES AS DDRS INHIBITORS
[French]
DÉRIVÉS DE PYRROLIDINE EN TANT QU'INHIBITEURS DE DDR
Applicants **
CHIESI FARMACEUTICI S.P.A.
Via Palermo 26/A
43122 Parma, IT
Inventors
CARZANIGA, Laura
c/o Chiesi Farmaceutici S.p.A.
Via Palermo 26/A
43122 Parma, IT
RANCATI, Fabio
c/o Chiesi Farmaceutici S.p.A.
Via Palermo 26/A
43122 Parma, IT
RIZZI, Andrea
c/o Chiesi Farmaceutici S.p.A.
Via Palermo 26/A
43122 Parma, IT
GHIDINI, Eleonora
c/o Chiesi Farmaceutici S.p.A.
Via Palermo 26/A
43122 Parma, IT
IOTTI, Nicolò
c/o Chiesi Farmaceutici S.p.A.
Via Palermo 26/A
43122 Reggio Emilia, IT
MAZZUCATO, Roberta
c/o Chiesi Farmaceutici S.p.A.
Via Palermo 26/A
43122 Parma, IT
LEVANTO, Stefano
c/o Chiesi Farmaceutici S.p.A.
Via Palermo 26/A
43122 Parma, IT
WHITTAKER, Ben Paul
c/o Chiesi Farmaceutici S.p.A.
Via Palermo 26/A
43122 Parma, IT
Priority Data
21203367.4
19.10.2021
EP
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
| * | |
| * | |
International Searching Authority |
EPO
* |
| Applicant's Legal Status |
Legal Entity
* |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Translation |
|
Recalculate
* The data is based on automatic recognition. Please verify and amend if necessary.
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing | 1759 | |
| EPO | Filing, Examination | 7458 | |
| Japan | Filing | 594 | |
| South Korea | Filing | 575 | |
| USA | Filing, Examination | 3760 |
Total: 14146 USD
The term for entry into the National Phase has expired. This quotation is for informational purposes only
Abstract[English]
The present invention relates to compounds of formula (I) inhibiting Discoidin Domain Receptors (DDR inhibitors), methods of preparing such compounds, intermediate compounds useful in such preparations, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful for instance in the treatment of many disorders associated with DDR mechanisms.[French]
La présente invention concerne des composés de formule (I) inhibant des récepteurs à domaine discoïdine (inhibiteurs de DDR), des procédés de préparation de tels composés, des composés intermédiaires utiles dans de telles préparations, des compositions pharmaceutiques les contenant et leur utilisation thérapeutique. Les composés de l'invention peuvent être utiles, par exemple, dans le traitement de nombreux troubles associés à des mécanismes DDR.