WO2023052543 - DETECTION OF BLADDER CANCER IN MALES

National phase entry:
Publication Number WO/2023/052543
Publication Date 06.04.2023
International Application No. PCT/EP2022/077186
International Filing Date 29.09.2022
Title **
[English] DETECTION OF BLADDER CANCER IN MALES
[French] DÉTECTION DU CANCER DE LA VESSIE CHEZ LES HOMMES
Applicants **
RANDOX LABORATORIES LTD
Inventors
FITZGERALD, Stephen Peter
RUDDOCK, Mark
LAMONT, John
Priority Data
2114088.4   01.10.2021   GB
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2047
EPO Filing, Examination, Granting8216
Japan Filing, Examination, Granting2155
South Korea Filing, Examination, Granting2071
USA Filing, Examination, Granting4740
MasterCard Visa
Total: 19,229

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] Haematuria is a considerable burden within primary and secondary care; too many haematuria patients are referred to secondary care for invasive and expensive investigations that could be managed in primary care. The current invention has identified biomarker combinations with prolactin and/or LASP-1 with utility for the diagnosis of bladder cancer in males. Using gender specific biomarker algorithms in combination with clinical risks that are associated with bladder cancer, would allow clinicians to better manage haematuria patients in primary care setting.[French] L'hématurie représente un fardeau considérable dans les soins primaires et secondaires; trop de patients souffrant d'hématurie sont envoyés en soins secondaires pour des recherches invasives et onéreuses qui pourraient être gérées lors de soins primaires. La présente invention a permis d'identifier des combinaisons de biomarqueurs avec la prolactine et/ou LASP-1 qui sont utiles pour le diagnostic du cancer de la vessie chez les hommes. L'utilisation d'algorithmes de biomarqueurs spécifiques au sexe en combinaison avec des risques cliniques qui sont associés au cancer de la vessie, permettrait aux cliniciens de mieux gérer les patients souffrant d'hématurie dans le cadre de soins primaires.