WO2023041524 - COMPOSITIONS AND METHODS FOR TREATING SYNUCLEINOPATHIES

National phase entry:
Publication Number WO/2023/041524
Publication Date 23.03.2023
International Application No. PCT/EP2022/075402
International Filing Date 13.09.2022
Title **
[English] COMPOSITIONS AND METHODS FOR TREATING SYNUCLEINOPATHIES
[French] COMPOSITIONS ET MÉTHODES DE TRAITEMENT DES SYNUCLÉINOPATHIES
Applicants **
H. LUNDBECK A/S Ottiliavej 9 2500 Valby, DK
Inventors
NIELSEN SØDERBERG, Josefine c/o H. Lundbeck A/S Ottiliavej 9 2500 Valby, DK
KALLUNKI, Pekka c/o H. Lundbeck A/S Ottiliavej 9 2500 Valby, DK
BUUR, Louise c/o H. Lundbeck A/S Ottiliavej 9 2500 Valby, DK
LARSEN, Frank c/o H. Lundbeck A/S Ottiliavej 9 2500 Valby, DK
PARSHAD, Henrik Rajesh Kumar c/o H. Lundbeck A/S Ottiliavej 9 2500 Valby, DK
MARKUSSEN, Anne Sofie c/o H. Lundbeck A/S Ottiliavej 9 2500 Valby, DK
MANNING, Mark Cornell 4630 Sorrel Lane Johnstown, Colorado 80534, US
KATAYAMA, Derrick Spencer 6773 Flintlock Rd Timnath, Colorado 80547, US
GAUDEN, Magdalena c/o Lonza Biologics plc 228 Bath Road Slough Berkshire SL1 4DX, GB
SMITH, John c/o Lonza Biologics plc 228 Bath Road Slough Berkshire SL1 4DX, GB
Priority Data
EP21197120   16.09.2021   EP
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Quotation for National Phase entry

Country StagesTotal
China Filing3350
EPO Filing, Examination22590
Japan Filing591
South Korea Filing575
USA Filing, Examination10210
MasterCard Visa

Total: 37316

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] The present invention relates to stable and low viscosity liquid pharmaceutical compositions comprising antibodies binding to human alpha synuclein and to methods for use of antibodies binding to human alpha synuclein for treating synucleinopathies or prodromal synucleinopathy, incl. suitable doses and/or dosing regimens. These antibodies for use in treatment of synucleinopathies or prodromal synucleinopathy may be formulated in the stable and low viscosity liquid pharmaceutical compositions of the invention.[French] La présente invention concerne des compositions pharmaceutiques liquides stables et à faible viscosité comprenant des anticorps se liant à l'alpha synucléine humaine et des méthodes d'utilisation d'anticorps se liant à l'alpha synucléine humaine pour traiter des synucléinopathies ou une synucléinopathie prodromique, y compris des doses et/ou des schémas posologiques appropriés. Ces anticorps destinés à être utilisés dans le traitement de synucléinopathies ou d'une synucléinopathie prodromique peuvent être formulés dans les compositions pharmaceutiques liquides stables et à faible viscosité de l'invention.
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