WO2023031082 - DEVICE FOR ADMINISTERING A PHARMACEUTICAL SUSPENSION

National phase entry:
Publication Number WO/2023/031082
Publication Date 09.03.2023
International Application No. PCT/EP2022/073887
International Filing Date 29.08.2022
Title **
[English] DEVICE FOR ADMINISTERING A PHARMACEUTICAL SUSPENSION
[French] DISPOSITIF D'ADMINISTRATION D'UNE SUSPENSION PHARMACEUTIQUE
Applicants **
NOVO NORDISK A/S Novo Alle 1 2880 Bagsværd, DK
Inventors
BENGTSSON, Henrik Novo Alle 1 2880 Bagsværd, DK
DEHLI, Jeppe, Ibsen Novo Alle 1 2880 Bagsværd, DK
HELBO, Janus Novo Alle 1 2880 Bagsværd, DK
EGENFELDT, Svend Novo Alle 1 2880 Bagsværd, DK
WINDUM, Jesper, Peter Novo Alle 1 2880 Bagsværd, DK
Priority Data
21194033.3   31.08.2021   EP
21210767.6   26.11.2021   EP
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Quotation for National Phase entry

Country StagesTotal
China Filing1450
EPO Filing, Examination5346
Japan Filing591
South Korea Filing607
USA Filing, Examination2710
MasterCard Visa

Total: 10704

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] The present invention provides a dose delivery device (1, 100, 200, 300, 400) comprising: a variable volume reservoir (10, 110, 210, 310, 410) holding a pharmaceutical suspension and comprising an outlet (12, 112, 212, 312, 412), a dose expelling mechanism adapted for activation to expel a volume of the pharmaceutical suspension through the outlet (12, 112, 5 212, 312, 412), and a dose preparation system comprising a preparation member (30, 130, 230, 330, 430) operable prior to activation of the dose expelling mechanism to enable administration of the volume of the pharmaceutical suspension to a subject, wherein the dose preparation system further comprises an agitation member (40, 140, 240, 340, 440) capable of agitating relative motion with respect to the variable volume reservoir (10, 110, 210, 310, 10 410), the agitating relative motion causing a re-suspending agitation of the pharmaceutical suspension, and wherein the agitation member (40, 140, 240, 340, 440) is operatively coupled with the preparation member (30, 130, 230, 330, 430) and configured to undergo said agitating relative motion in response to the operation of the preparation member (30, 130, 230, 330, 430).[French] La présente invention concerne un dispositif de distribution de dose (1, 100, 200, 300, 400) comprenant : un réservoir à volume variable (10, 110, 210, 310, 410) contenant une suspension pharmaceutique et comprenant une sortie (12, 112, 212, 312, 412), un mécanisme d'expulsion de dose conçu pour être activé afin d'expulser un volume de la suspension pharmaceutique à travers la sortie (12, 112, 5 212, 312, 412), et un système de préparation de dose comprenant un élément de préparation (30, 130, 230, 330, 430) pouvant fonctionner avant l'activation du mécanisme d'expulsion de dose pour permettre l'administration du volume de la suspension pharmaceutique à un sujet, le système de préparation de dose comprenant en outre un élément d'agitation (40, 140, 240, 340, 440) apte à agiter un mouvement relatif par rapport au réservoir à volume variable (10, 110, 210, 310, 10 410), le mouvement relatif d'agitation provoquant une agitation de remise en suspension de la suspension pharmaceutique, et l'élément d'agitation (40, 140, 240, 340, 440) est fonctionnellement couplé à l'élément de préparation (30, 130, 230, 330, 430) et configuré pour subir ledit mouvement relatif d'agitation en réponse au fonctionnement de l'élément de préparation (30, 130, 230, 330, 430).
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