WO2023017072 - RISK PREDICTION MODEL FOR PROSTATE CANCER

National phase entry:
Publication Number WO/2023/017072
Publication Date 16.02.2023
International Application No. PCT/EP2022/072425
International Filing Date 10.08.2022
Title **
[English] RISK PREDICTION MODEL FOR PROSTATE CANCER
[French] MODÈLE DE PRÉDICTION DE RISQUE POUR LE CANCER DE LA PROSTATE
Applicants **
RANDOX LABORATORIES LTD 55 The Diamond Road Crumlin Crumlin Antrim BT29 4QY, GB
Inventors
FITZGERALD, Stephen Peter 55 The Diamond Road Crumlin Antrim BT29 4QY, GB
RUDDOCK, Mark 55 The Diamond Road Crumlin Antrim BT29 4QY, GB
LAMONT, John 55 The Diamond Road Crumlin Antrim BT29 4QY, GB
MCKENNA, Declan School of Biomedical Sciences University of Ulster Cromore Road Coleraine Londonderry BT52 1SA, GB
Priority Data
2111635.5   13.08.2021   GB
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Quotation for National Phase entry

Country StagesTotal
China Filing961
EPO Filing, Examination4636
Japan Filing595
South Korea Filing574
USA Filing, Examination2710
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Total: 9476

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] Single markers lack both sensitivity and specificity to stratify risk of PCa in patients who present with elevated tPSA and abnormal DRE. The novel combination of serum markers identified in this study could be employed to help triage patients into 'low' and 'high' risk categories, allowing general practitioners (GPs) to improve management of patients in primary care settings and potentially reducing the number of referrals for unnecessary, invasive, and costly treatments.[French] Des marqueurs uniques sont dépourvus à la fois de sensibilité et de spécificité pour stratifier le risque de cancer de la prostate chez des patients qui présentent un tPSA élevé et un DRE anormal. La nouvelle combinaison de marqueurs sériques identifiés dans cette étude pourrait être utilisée pour aider les patients au triage dans des catégories de risque'bas'et'haut ', ce qui permet aux praticiens généraux (GPs) d'améliorer la gestion de patients dans l'établissement de soins primaires et réduire potentiellement le nombre de recommandations pour des traitements inutiles, invasifs et coûteux.
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