WO2023006581 - A METHOD AND REAGENTS FOR ENHANCING THE CHEMILUMINESCENT SIGNAL
National phase entry:
Publication Number
WO/2023/006581
Publication Date
02.02.2023
International Application No.
PCT/EP2022/070522
International Filing Date
21.07.2022
Title **
[English]
A METHOD AND REAGENTS FOR ENHANCING THE CHEMILUMINESCENT SIGNAL
[French]
PROCÉDÉ ET RÉACTIFS POUR AMPLIFIER LE SIGNAL CHIMIOLUMINESCENT
Applicants **
EUROIMMUN MEDIZINISCHE LABORDIAGNOSTIKA AG
Seekamp 31
23560 Lübeck, DE
Inventors
THEUSER, Matthias
23560 Lübeck, DE
KOMOROWSKI, Lars
23560 Lübeck, DE
DAMMERMANN, Antje
23560 Lübeck, DE
BAUMERT, Kathrin
23560 Lübeck, DE
HOLSTE, Mareike
23560 Lübeck, DE
HINKELAMMERT, Marcel
23560 Lübeck, DE
Priority Data
21188638.7
29.07.2021
EP
Application details
| Total Number of Claims/PCT | * |
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| Number of Drawings | * |
| Pages for Publication | * |
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International Searching Authority |
EPO
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Translation |
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing | 1329 | |
| EPO | Filing, Examination | 5232 | |
| Japan | Filing | 589 | |
| South Korea | Filing | 575 | |
| USA | Filing, Examination | 3310 |
Total: 11035 USD
The term for entry into the National Phase has expired. This quotation is for informational purposes only
Abstract[English]
The present invention relates to a method for enhancing the chemiluminescent signal of a chemiluminogenic compound in a chemiluminescent reaction mixture in a chemiluminescent reaction which comprises oxidizing the chemiluminogenic compound in the presence of an effective amount of an enhancer to obtain an enhanced chemiluminescent signal, use of a compound selected from the group consisting of quarternary amine cationic substances of formula (I) for enhancing the chemiluminescent signal of an acridinium compound, preferably an acridinium ester or an acridinium sulfonamide, in a chemiluminescent reaction, preferably in a chemiluminescent immunoassay, a related chemiluminescent composition and a related kit.[French]
La présente invention concerne un procédé pour amplifier le signal chimioluminescent d'un composé chimioluminogène dans un mélange réactionnel chimioluminescent dans une réaction chimioluminescente qui comprend l'oxydation du composé chimioluminogène en présence d'une quantité efficace d'un amplificateur pour obtenir un signal chimioluminescent amplifié, l'utilisation d'un composé choisi dans le groupe constitué par les substances cationiques d'amine quaternaire de formule (I) pour amplifier le signal chimioluminescent d'un composé d'acridinium, de préférence un ester d'acridinium ou un sulfamide d'acridinium, dans une réaction chimioluminescente, de préférence dans un dosage immunologique chimioluminescent, une composition chimioluminescente associée et un kit associé.