WO2023104327 - COMBINATION OF 5-AMINO-2,3-DIHYDRO-1,4-PHTALAZINEDIONE AND A 6'-METHOXYCINCHONAN-9-OL FOR USE IN THE TREATMENT OF CORONAVIRAL INFECTIONS
National phase entry:
Publication Number
WO/2023/104327
Publication Date
15.06.2023
International Application No.
PCT/EP2022/000110
International Filing Date
08.12.2022
Title **
[English]
COMBINATION OF 5-AMINO-2,3-DIHYDRO-1,4-PHTALAZINEDIONE AND A 6'-METHOXYCINCHONAN-9-OL FOR USE IN THE TREATMENT OF CORONAVIRAL INFECTIONS
[French]
COMBINAISON DE 5-AMINO-2,3-DIHYDRO-1,4-PHTALAZINEDIONE ET D'UN 6'-MÉTHOXYCINCHONANE-9-OL POUR UNE UTILISATION DANS LE TRAITEMENT D'INFECTIONS CORONAVIRALES
Applicants **
METRIOPHARM AG
Europaallee 41
8021 Zürich, CH
Inventors
BRYSCH, Wolfgang
Rabenhorststr. 7
13505 Berlin, DE
SCHUMANN, Sara
Hauptstr. 1
14554 Seddiner See, DE
LUDESCHER, Beate
Dannenwalder Weg 58
13439 Berlin, DE
VON WEGERER, Jörg
Ruhlebener Str. 20
13597 Berlin, DE
SETZ, Christian
Erlanger Straße 5
90562 Kalchreuth, DE
SCHUBERT, Ulrich
Rothehofstal 1
07646 Trockenborn-Wolfersdorf, DE
Priority Data
21000346.3
08.12.2021
EP
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
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| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
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International Searching Authority |
EPO
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Translation |
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Recalculate
* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing | 1273 | |
| EPO | Filing, Examination | 5389 | |
| Japan | Filing | 589 | |
| South Korea | Filing | 575 | |
| USA | Filing, Examination | 2710 |

Total: 10536 USD
The term for entry into the National Phase has expired. This quotation is for informational purposes only
Abstract[English]
The present application relates to a combination of 5-amino-2,3-dihydro-1,4- phthalazinedione or one of its pharmaceutically acceptable salts and a 6'-methoxycinchonan- 9-ol or a pharmaceutically acceptable salt thereof for use in the prevention or treatment of coronaviral infections. In particular, the invention relates to a combination of 5-amino-2,3- dihydro-1,4-phthalazinedione sodium salt and quinine or quinidine for said purposes. Pharmaceutical compositions and advantageous formulation techniques are disclosed.[French]
La présente invention concerne une combinaison de 5-amino-2,3-dihydro-1,4-phtalazinedione ou d'un de ses sels pharmaceutiquement acceptables et d'un 6'-méthoxycinchonane-9-ol ou d'un sel pharmaceutiquement acceptable de celui-ci, destinée à être utilisée dans la prévention ou le traitement d'infections coronavirales. En particulier, l'invention concerne une combinaison de sel de sodium de 5-amino-2,3-dihydro-1,4-phtalazinedione et de quinine ou de quinidine pour lesdites applications. L'invention concerne également des compositions pharmaceutiques et des techniques de formulation avantageuses.