WO2023104327 - COMBINATION OF 5-AMINO-2,3-DIHYDRO-1,4-PHTALAZINEDIONE AND A 6'-METHOXYCINCHONAN-9-OL FOR USE IN THE TREATMENT OF CORONAVIRAL INFECTIONS

National phase entry:
Publication Number WO/2023/104327
Publication Date 15.06.2023
International Application No. PCT/EP2022/000110
International Filing Date 08.12.2022
Title **
[English] COMBINATION OF 5-AMINO-2,3-DIHYDRO-1,4-PHTALAZINEDIONE AND A 6'-METHOXYCINCHONAN-9-OL FOR USE IN THE TREATMENT OF CORONAVIRAL INFECTIONS
[French] COMBINAISON DE 5-AMINO-2,3-DIHYDRO-1,4-PHTALAZINEDIONE ET D'UN 6'-MÉTHOXYCINCHONANE-9-OL POUR UNE UTILISATION DANS LE TRAITEMENT D'INFECTIONS CORONAVIRALES
Applicants **
METRIOPHARM AG Europaallee 41 8021 Zürich, CH
Inventors
BRYSCH, Wolfgang Rabenhorststr. 7 13505 Berlin, DE
SCHUMANN, Sara Hauptstr. 1 14554 Seddiner See, DE
LUDESCHER, Beate Dannenwalder Weg 58 13439 Berlin, DE
VON WEGERER, Jörg Ruhlebener Str. 20 13597 Berlin, DE
SETZ, Christian Erlanger Straße 5 90562 Kalchreuth, DE
SCHUBERT, Ulrich Rothehofstal 1 07646 Trockenborn-Wolfersdorf, DE
Priority Data
21000346.3   08.12.2021   EP
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Quotation for National Phase entry

Country StagesTotal
China Filing1273
EPO Filing, Examination5389
Japan Filing589
South Korea Filing575
USA Filing, Examination2710
MasterCard Visa

Total: 10536

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] The present application relates to a combination of 5-amino-2,3-dihydro-1,4- phthalazinedione or one of its pharmaceutically acceptable salts and a 6'-methoxycinchonan- 9-ol or a pharmaceutically acceptable salt thereof for use in the prevention or treatment of coronaviral infections. In particular, the invention relates to a combination of 5-amino-2,3- dihydro-1,4-phthalazinedione sodium salt and quinine or quinidine for said purposes. Pharmaceutical compositions and advantageous formulation techniques are disclosed.[French] La présente invention concerne une combinaison de 5-amino-2,3-dihydro-1,4-phtalazinedione ou d'un de ses sels pharmaceutiquement acceptables et d'un 6'-méthoxycinchonane-9-ol ou d'un sel pharmaceutiquement acceptable de celui-ci, destinée à être utilisée dans la prévention ou le traitement d'infections coronavirales. En particulier, l'invention concerne une combinaison de sel de sodium de 5-amino-2,3-dihydro-1,4-phtalazinedione et de quinine ou de quinidine pour lesdites applications. L'invention concerne également des compositions pharmaceutiques et des techniques de formulation avantageuses.
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