WO2026124314 - METHOD FOR OBTAINING GLYPHOSATE-RESISTANT TRAIT WITHOUT FITNESS COST
National phase entry is expected:
Publication Number
WO/2026/124314
Publication Date
18.06.2026
International Application No.
PCT/CN2025/139584
International Filing Date
03.12.2025
Title **
[English]
METHOD FOR OBTAINING GLYPHOSATE-RESISTANT TRAIT WITHOUT FITNESS COST
[French]
PROCÉDÉ PERMETTANT D'OBTENIR UN TRAIT DE RÉSISTANCE AU GLYPHOSATE SANS COÛT ADAPTATIF
[Chinese]
一种获得无适生性代价抗草甘膦性状的方法
Applicants **
QINGDAO KINGAGROOT SEED SCIENCE CO., LTD.
Inventors
YUAN, Kun
MO, Sudong
WANG, Jiyao
WANG, Lei
LIAN, Lei
LI, Huarong
JIANG, Linjian
Priority Data
202411798433.6
09.12.2024
CN
202511556974.2
28.10.2025
CN
Application details
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International Searching Authority |
CNIPA
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Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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Send the Letters Patent by Courier
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 1631 | |
| EPO | Filing, Examination, Granting | 11558 | |
| Japan | Filing, Examination, Granting | 1968 | |
| South Korea | Filing, Examination, Granting | 1770 | |
| USA | Filing, Examination, Granting | 4740 |
Total:
21,667
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Abstract[English]
Provided is a method for obtaining a glyphosate-resistant trait without a fitness cost. The method comprises the following steps: producing at least two copies of an endogenous epsps gene by means of in planta chromosomal segment duplication, wherein a point mutation conferring resistance to glyphosate occurs in at least one copy of the epsps gene, and at least one copy remains wild-type. Compared with a wild-type plant, the plant obtained by the method exhibits no significant loss of agronomic traits, demonstrates significantly improved resistance to glyphosate-based herbicides, and offers great application value.[French]
La présente invention concerne un procédé permettant d'obtenir un trait de résistance au glyphosate sans coût adaptatif. Le procédé consiste notamment à produire au moins deux copies d'un gène epsps endogène par duplication de segments chromosomiques in planta, une mutation ponctuelle conférant une résistance au glyphosate survenant dans au moins une copie du gène epsps, tandis qu'au moins une copie reste de type sauvage. Par comparison avec une plante de type sauvage, la plante obtenue selon le procédé ne présente aucune perte significative de ses caractéristiques agronomiques, fait preuve d'une résistance nettement améliorée aux herbicides à base de glyphosate et offre un grand intérêt pratique.[Chinese]
提供一种获得无适生性代价抗草甘膦性状的方法。所述方法包括以下步骤：在植物体内通过染色体片段加倍产生至少两个拷贝的内源epsps基因，其中至少一个拷贝的epsps基因上产生抗草甘膦的点突变并且至少一个拷贝保持野生型。所述方法获得的植物与野生型植物相比无明显农艺性状损失，对草甘膦除草剂的抗性显著提高，具有重大应用价值。