WO2026067609 - PEGYLATED LIPID MODIFIED WITH TARGETING LIGAND, RELATED COMPOSITION AND USE THEREOF

National phase entry is expected:
Publication Number WO/2026/067609
Publication Date 02.04.2026
International Application No. PCT/CN2025/124304
International Filing Date 26.09.2025
Title **
[English] PEGYLATED LIPID MODIFIED WITH TARGETING LIGAND, RELATED COMPOSITION AND USE THEREOF
[French] LIPIDE PEGYLÉ MODIFIÉ AVEC UN LIGAND DE CIBLAGE, COMPOSITION ASSOCIÉE ET UTILISATION ASSOCIÉE
[Chinese] 靶向配体修饰的聚乙二醇化脂质,相关的组合物及其应用
Applicants **
XIAMEN SINOPEG BIOTECH CO., LTD
Inventors
LIN, Sheng
CHEN, Dandan
WANG, Ailan
WEI, Guohua
LIN, Congming
ZHU, Qi
WENG, Wengui
LIU, Chao
Priority Data
202411350428.9   26.09.2024   CN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2657
EPO Filing, Examination, Granting19521
Japan Filing, Examination, Granting2493
South Korea Filing, Examination, Granting2861
USA Filing, Examination, Granting6390
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Total: 33,922
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Abstract[English] and M are divalent linking groups. The targeting PEGylated lipid of the present invention significantly improves the in vitro and in vivo targeting effects of lipid nanoparticles, and can achieve more efficient delivery of liver-targeting drugs.[French] et M étant des groupes de liaison divalents. Le lipide pegylé de ciblage de la présente invention améliore significativement les effets de ciblage in vitro et in vivo de nanoparticules lipidiques, et peut procurer une administration plus efficace de médicaments ciblant le foie.[Chinese] 和M为二价连接基。本发明的靶向性聚乙二醇化脂质显著提升了脂质纳米粒的体外和体内的靶向效果,可实现更为高效的肝靶向药物递送。