WO2026103337 - NOVEL SUBSTITUTED HETEROCYCLIC COMPOUND AS APELIN RECEPTOR MODULATOR

National phase entry is expected:
Publication Number WO/2026/103337
Publication Date 21.05.2026
International Application No. PCT/CN2025/122825
International Filing Date 22.09.2025
Title **
[English] NOVEL SUBSTITUTED HETEROCYCLIC COMPOUND AS APELIN RECEPTOR MODULATOR
[French] NOUVEAU COMPOSÉ HÉTÉROCYCLIQUE SUBSTITUÉ EN TANT QUE MODULATEUR DU RÉCEPTEUR DE L'APÉLINE
[Chinese] 作为APELIN受体调节剂的新型取代杂环类化合物
Applicants **
MINDRANK THERAPEUTICS (SUZHOU) NEW DRUG RESEARCH AND DEVELOPMENT CO., LTD
Inventors
ZHANG, Long
Priority Data
202411630773.8   15.11.2024   CN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2130
EPO Filing, Examination, Granting13622
Japan Filing, Examination, Granting2029
South Korea Filing, Examination, Granting1870
USA Filing, Examination, Granting5190
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Total: 24,841
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Abstract[English] Disclosed in the present invention is a compound having significant Apelin receptor modulation activity, and specifically disclosed is a compound represented by the following formula (I), or a pharmaceutically acceptable salt, solvate, hydrate, isotopologue, or isomer thereof.[French] La présente invention concerne un composé présentant une activité significative de modulation du récepteur de l'apéline, et concerne plus particulièrement un composé représenté par la formule (I) suivante, ou un sel, solvate, hydrate, isotopologue ou isomère pharmaceutiquement acceptable de celui-ci.[Chinese] 本发明公开了具有显著的Apelin受体调节活性的化合物,具体公开了如下式(I)结构所示化合物或其药学上可接受的盐、溶剂合物、水合物、同位素取代物或其异构体。

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