WO2026021011 - ARYL TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF
National phase entry is expected:
Publication Number
WO/2026/021011
Publication Date
29.01.2026
International Application No.
PCT/CN2025/099565
International Filing Date
06.06.2025
Title **
[English]
ARYL TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF
[French]
DÉRIVÉ TRICYCLIQUE D'ARYLE, SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION
[Chinese]
芳基三环类衍生物及其制备方法和用途
Applicants **
ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.
SHANGHAI ARYL PHARMTECH CO., LTD.
Inventors
WU, Nuoyi
QIU, Haibo
GUO, Ze
MAO, Wentao
CHEN, Ahuan
ZHAO, Weifeng
YE, Cheng
YU, Mingfeng
ZHENG, Xiaohe
ZHOU, Houjiang
Priority Data
202411010302.7
26.07.2024
CN
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
| * | |
| Number of Office Actions | * |
| * | |
International Searching Authority |
CNIPA
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
* |
| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Patent Delivery |
Send the Letters Patent by Courier
* |
| Translation |
|
* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 1944 | |
| EPO | Filing, Examination, Granting | 13679 | |
| Japan | Filing, Examination, Granting | 2247 | |
| South Korea | Filing, Examination, Granting | 2336 | |
| USA | Filing, Examination, Granting | 4740 |
Total:
24,946
Contact Us
Abstract[English]
Provided are an aryl tricyclic derivative, a preparation method therefor, and a use of a pharmaceutical composition containing the derivative in medicine. Specifically, provided are an aryl tricyclic derivative represented by general formula (I), a preparation method therefor and a pharmaceutically acceptable salt thereof, and a use of the aryl tricyclic derivative and the pharmaceutically acceptable salt as a therapeutic agent, especially as a Kv1.3 potassium ion channel inhibitor, wherein the definition of each substituent in general formula (I) is the same as that in the description.[French]
L'invention concerne un dérivé tricyclique d'aryle, son procédé de préparation et l'utilisation d'une composition pharmaceutique contenant le dérivé en médecine. Plus particulièrement, l'invention concerne un dérivé tricyclique d'aryle représenté par la formule générale (I), son procédé de préparation et un sel pharmaceutiquement acceptable de celui-ci, et une utilisation du dérivé tricyclique d'aryle et du sel pharmaceutiquement acceptable en tant qu'agent thérapeutique, en particulier en tant qu'inhibiteur des canaux potassiques Kv1.3, la définition de chaque substituant dans la formule générale (I) étant la même que celle dans la description.[Chinese]
提供一种芳基三环类衍生物、其制备方法及含有该衍生物的药物组合物在医药上的应用。具体而言，提供一种通式(I)所示的芳基三环类衍生物、其制备方法及其可药用的盐，以及它们作为治疗剂，特别是作为Kv1.3钾离子通道抑制剂的用途，其中通式(I)中的各取代基的定义与说明书中的定义相同。