WO2025247371 - PROTEIN DEGRADATION-TARGETING CHIMERA COMPOUNDS TARGETING BRAF, AND COMPOSITION AND USE THEREOF
National phase entry is expected:
Publication Number
WO/2025/247371
Publication Date
04.12.2025
International Application No.
PCT/CN2025/098336
International Filing Date
30.05.2025
Title **
[English]
PROTEIN DEGRADATION-TARGETING CHIMERA COMPOUNDS TARGETING BRAF, AND COMPOSITION AND USE THEREOF
[French]
COMPOSÉS CHIMÈRES CIBLANT LA DÉGRADATION DE PROTÉINES CIBLANT LE BRAF, ET COMPOSITION ET UTILISATION ASSOCIÉES
[Chinese]
靶向BRAF蛋白降解靶向嵌合体类化合物及其组合物及用途
Applicants **
SHENZHEN TARGETRX, INC.
Inventors
WANG, Yihan
ZHAO, Jiuyang
AI, Yixin
Priority Data
202410704324.7
31.05.2024
CN
202510680566.1
23.05.2025
CN
Application details
| Total Number of Claims/PCT | * |
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| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
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International Searching Authority |
CNIPA
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
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| * | |
| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 8297 | |
| EPO | Filing, Examination, Granting | 140100 | |
| Japan | Filing, Examination, Granting | 4940 | |
| South Korea | Filing, Examination, Granting | 9568 | |
| USA | Filing, Examination, Granting | 29240 |
Total:
192,145
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Abstract[English]
The present invention relates to protein degradation-targeting chimera compounds having a degradation and/or inhibitory activity against mutant BRAF, and further relates to a pharmaceutical composition containing same, and a preparation method therefor and the use thereof.[French]
La présente invention concerne des composés chimères ciblant la dégradation de protéines ayant une activité de dégradation et/ou inhibitrice contre le BRAF mutant, et concerne en outre une composition pharmaceutique les contenant, leur procédé de préparation et leur utilisation.[Chinese]
本发明涉及对突变BRAF具有降解和/或抑制活性的蛋白降解靶向嵌合体类化合物，还涉及包含它们的药物组合物，以及它们的制备方法和用途。