WO2025201294 - INDOLE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF IN UP-REGULATION OF MIR

National phase entry is expected:
Publication Number WO/2025/201294
Publication Date 02.10.2025
International Application No. PCT/CN2025/084599
International Filing Date 25.03.2025
Title **
[English] INDOLE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF IN UP-REGULATION OF MIR
[French] COMPOSÉ INDOLE, SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION DANS LA RÉGULATION POSITIVE DE MIR
[Chinese] 一种吲哚类化合物及其制备方法与miR上调应用
Applicants **
SHENZHEN SALUBRIS PHARMACEUTICALS CO., LTD
Inventors
HU, Hao
LU, Yinsuo
WU, Junjun
CHU, Cuiping
XIAO, Ying
LI, Hongchao
SU, Jianhong
Priority Data
202410356878.2   26.03.2024   CN
202410619490.7   17.05.2024   CN
202410897181.6   04.07.2024   CN
202411012743.0   25.07.2024   CN
202411346727.5   25.09.2024   CN
202510068605.2   15.01.2025   CN
202510329014.6   19.03.2025   CN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2040
EPO Filing, Examination, Granting11820
Japan Filing, Examination, Granting2061
South Korea Filing, Examination, Granting2129
USA Filing, Examination, Granting4740
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Total: 22,790
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Abstract[English] The present invention relates to the technical field of chemical medicines, and relates to a compound represented by general formula (Ia), or a racemate thereof, or an isomer thereof, or a pharmaceutically acceptable salt thereof, and a use thereof in the preparation of a drug for treating related diseases by regulating the miRNA level.[French] La présente invention se rapporte au domaine technique des médicaments chimiques, et concerne un composé représenté par la formule générale (Ia), ou un racémate de celui-ci, ou un isomère de celui-ci, ou un sel pharmaceutiquement acceptable de celui-ci, et une utilisation de celui-ci dans la préparation d'un médicament pour le traitement de maladies associées par régulation du taux de miARN.[Chinese] 本发明属于化学药物技术领域,涉及一种通式(Ia)所示的化合物,或其消旋体、或其异构体、或其可药用的盐,以及在制备用于治疗调节miRNA水平相关疾病的药物用途。