WO2025201277 - METHOD FOR TREATING DYSLIPIDEMIA WITH ANGIOPOIETIN-LIKE 3 (ANGPTL3) -TARGETED RNAI AGENTS
National phase entry is expected:
Publication Number
WO/2025/201277
Publication Date
02.10.2025
International Application No.
PCT/CN2025/084552
International Filing Date
25.03.2025
Title **
[English]
METHOD FOR TREATING DYSLIPIDEMIA WITH ANGIOPOIETIN-LIKE 3 (ANGPTL3) -TARGETED RNAI AGENTS
[French]
MÉTHODE DE TRAITEMENT DE LA DYSLIPIDÉMIE AVEC DES AGENTS ARNI CIBLANT L'ANGIOPOÏÉTINE 3 (ANGPTL3)
Applicants **
SHANGHAI ARGO BIOPHARMACEUTICAL CO., LTD.
Inventors
SHU, Dongxu
SHAO, Pengcheng Patrick
LI, Yuqiong
HE, Yafeng
Priority Data
PCT/CN2024/083497
25.03.2024
CN
PCT/CN2024/124851
15.10.2024
CN
Application details
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International Searching Authority |
CNIPA
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 3836 | |
| EPO | Filing, Examination, Granting | 52132 | |
| Japan | Filing, Examination, Granting | 3725 | |
| South Korea | Filing, Examination, Granting | 5559 | |
| USA | Filing, Examination, Granting | 15590 |
Total:
80,842
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Abstract[English]
It relates to methods of inhibiting the expression of an ANGPTL3 gene in a subject, as well as therapeutic and prophylactic methods for treating subjects having a lipid disorder, such as a hyperlipidemia using RNAi agents, e.g., double-stranded RNAi agents, targeting the ANGPTL3 gene.[French]
L'invention concerne des méthodes d'inhibition de l'expression d'un gène ANGPTL3 chez un sujet, ainsi que des méthodes thérapeutiques et prophylactiques pour traiter des sujets ayant un trouble lipidique, tel qu'une hyperlipidémie à l'aide d'agents ARNi, par exemple, des agents ARNi double brin, ciblant le gène ANGPTL3.