WO2025195445 - MULTI-SPECIFIC ANTIBODY SPECIFICALLY BINDING TO LIGHT AND TSLP, AND COMPOSITION AND USE THEREOF

National phase entry is expected:
Publication Number WO/2025/195445
Publication Date 25.09.2025
International Application No. PCT/CN2025/083666
International Filing Date 20.03.2025
Title **
[English] MULTI-SPECIFIC ANTIBODY SPECIFICALLY BINDING TO LIGHT AND TSLP, AND COMPOSITION AND USE THEREOF
[French] ANTICORPS MULTI-SPÉCIFIQUE SE LIANT DE MANIÈRE SPÉCIFIQUE À LIGHT ET TSLP, COMPOSITION ET UTILISATION ASSOCIÉES
[Chinese] 特异性结合LIGHT和TSLP的多特异性抗体以及组合物及其应用
Applicants **
BEIJING SOLOBIO GENETECHNOLOGY CO., LTD.
Inventors
WANG, Guangfei
LI, Zhong
ZHANG, Si
LIU, Hongyang
ZHANG, Miaomin
WANG, Guowu
YU, Debin
CUI, Jinglan
Priority Data
PCT/CN2024/082930   21.03.2024   CN
PCT/CN2024/119606   19.09.2024   CN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2572
EPO Filing, Examination, Granting17872
Japan Filing, Examination, Granting2400
South Korea Filing, Examination, Granting2695
USA Filing, Examination, Granting5790
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Total: 31,329
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Abstract[English] The present invention relates to a multi-specific antibody or antigen-binding fragment specifically binding to LIGHT and TSLP, a composition comprising an antibody or antigen-binding fragment specifically binding to LIGHT and an antibody or antigen-binding fragment specifically binding to TSLP, and a pharmaceutical composition comprising the multi-specific antibody or composition, a preparation method for the pharmaceutical composition and a use thereof, including a method for using the pharmaceutical composition to prevent and treat inflammatory diseases, respiratory diseases, or autoimmune diseases.[French] La présente invention concerne un anticorps multi-spécifique ou un fragment de liaison à l'antigène se liant de manière spécifique à LIGHT et TSLP, une composition comprenant un anticorps ou un fragment de liaison à l'antigène se liant de manière spécifique à LIGHT et un anticorps ou un fragment de liaison à l'antigène se liant de manière spécifique à TSLP, et une composition pharmaceutique comprenant l'anticorps ou la composition multi-spécifique, un procédé de préparation de la composition pharmaceutique et une utilisation associée, comprenant un procédé d'utilisation de la composition pharmaceutique pour prévenir et traiter des maladies inflammatoires, des maladies respiratoires ou des maladies auto-immunes.[Chinese] 涉及特异性结合LIGHT和TSLP的多特异性抗体或抗原结合片段,包含特异性结合LIGHT的抗体或抗原结合片段和特异性结合TSLP的抗体或抗原结合片段的组合物,以及包含上述多特异性抗体或组合物的药物组合物、其制备方法和用途,包括用其预防和治疗炎症性、呼吸或自身免疫性疾病的方法。