WO2025131035 - BASE EDITING TOOL AND USE THEREOF
National phase entry is expected:
Publication Number
WO/2025/131035
Publication Date
26.06.2025
International Application No.
PCT/CN2024/140869
International Filing Date
20.12.2024
Title **
[English]
BASE EDITING TOOL AND USE THEREOF
[French]
OUTIL D'ÉDITION DE BASES ET SON UTILISATION
[Chinese]
一种碱基编辑工具及其应用
Applicants **
SHANDONG SHUNFENG BIOTECHNOLOGY CO. LTD.
Inventors
LIANG, Yafeng
Priority Data
202311769067.7
21.12.2023
CN
202410713487.1
04.06.2024
CN
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
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| Number of Office Actions | * |
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International Searching Authority |
CNIPA
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Patent Delivery |
Send the Letters Patent by Courier
* |
| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 1740 | |
| EPO | Filing, Examination, Granting | 11677 | |
| Japan | Filing, Examination, Granting | 2091 | |
| South Korea | Filing, Examination, Granting | 2037 | |
| USA | Filing, Examination, Granting | 4740 |
Total:
22,285
The term for entry into the National Phase has expired. This quotation is for informational purposes only
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Abstract[English]
The present invention belongs to the field of nucleic acid editing, and particularly to the technical field of clustered regulatory interspaced short palindromic repeats (CRISPR). Specifically, provided in the present invention is an adenosine deaminase, which is fused with a DNA binding protein and can be used for single-base editing of a target nucleic acid, and has wide application prospects.[French]
La présente invention relève du domaine de l'édition des acides nucléiques, et plus particulièrement du domaine technique des courtes répétitions palindromiques groupées et régulièrement espacées (CRISPR). La présente invention porte spécifiquement sur une adénosine désaminase fusionnée avec une protéine de liaison à l'ADN, pouvant être utilisée pour l'édition d'une seule base d'un acide nucléique cible, et présentant de vastes perspectives d'application.[Chinese]
本发明属于核酸编辑领域，特别是规律成簇的间隔短回文重复(CRISPR)技术领域。具体而言，本发明提供了一种腺苷脱氨酶，使其与DNA结合蛋白融合，能够用于靶核酸的单碱基编辑，具有广泛的应用前景。