WO2025098503 - CEREBLON E3 UBIQUITIN LIGASE INHIBITOR

National phase entry is expected:
Publication Number WO/2025/098503
Publication Date 15.05.2025
International Application No. PCT/CN2024/131100
International Filing Date 08.11.2024
Title **
[English] CEREBLON E3 UBIQUITIN LIGASE INHIBITOR
[French] INHIBITEUR DE L'UBIQUITINE LIGASE E3 CÉRÉBLON
[Chinese] 小脑蛋白E3泛素连接酶抑制剂
Applicants **
GAN & LEE PHARMACEUTICALS CO., LTD.
Inventors
XU, Fuming
CHEN, Wenmin
ZHOU, Guan
XUE, Wei
DING, Yongzheng
LIU, Xiaobing
LI, Xiaoguang
Priority Data
202311479565.8   08.11.2023   CN
202311804797.6   26.12.2023   CN
202411250508.7   06.09.2024   CN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting3375
EPO Filing, Examination, Granting23547
Japan Filing, Examination, Granting2616
South Korea Filing, Examination, Granting3199
USA Filing, Examination, Granting7640
MasterCard Visa
Total: 40,377

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] The present invention relates to a new human cereblon (CRBN) E3 ubiquitin ligase inhibitor, which can be used for preparing PROTAC molecules. The CRBN E3 ubiquitin ligase inhibitor and the PROTAC molecules can be used for treating cancer and other diseases.[French] La présente invention concerne un nouvel inhibiteur de l'ubiquitine ligase E3 céréblon (CRBN) humaine, qui peut être utilisé pour préparer des molécules PROTAC. L'inhibiteur de l'ubiquitine ligase E3 CRBN et les molécules PROTAC peuvent être utilisés pour traiter le cancer et d'autres maladies.[Chinese] 本发明涉及一种新的人小脑蛋白(CRBN)E3泛素连接酶抑制剂,其可用于制备PROTAC分子。CRBN E3泛素连接酶抑制剂和PROTAC分子可用于治疗癌症和其他疾病。

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