WO2025002221 - MULTI-SPECIFIC ANTIBODIES COMPRISING ANTIGEN-BINDING DOMAINS SPECIFICALLY RECOGNIZING C5AR1 AND GM-CSFR ALPHA

National phase entry:
Publication Number WO/2025/002221
Publication Date 02.01.2025
International Application No. PCT/CN2024/101864
International Filing Date 27.06.2024
Title **
[English] MULTI-SPECIFIC ANTIBODIES COMPRISING ANTIGEN-BINDING DOMAINS SPECIFICALLY RECOGNIZING C5AR1 AND GM-CSFR ALPHA
[French] ANTICORPS MULTI-SPÉCIFIQUES COMPRENANT DES DOMAINES DE LIAISON À L'ANTIGÈNE RECONNAISSANT DE MANIÈRE SPÉCIFIQUE C5AR1 ET GM-CSFR ALPHA
Applicants **
STAIDSON (BEIJING) BIOPHARMACEUTICALS CO., LTD.
Inventors
HE, Chong
ZHAI, Wenwu
ZHOU, Zhiwen
STRAINIC, Michael George
YUAN, Ping
YI, Zuoan
Priority Data
PCT/CN2023/102813   27.06.2023   CN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting3680
EPO Filing, Examination, Granting27425
Japan Filing, Examination, Granting2854
South Korea Filing, Examination, Granting3590
USA Filing, Examination, Granting10290
MasterCard Visa
Total: 47,839

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] Provides multi-specific (e.g., bispecific) antibodies that specifically recognize C5aR1 and GM-CSFRα, and pharmaceutical compositions comprising multi-specific (e.g., bispecific) antibodies that specifically recognize C5aR1 and GM-CSFRα. Also provided are methods of making and using these antibodies.[French] L'invention concerne des anticorps multispécifiques (par exemple, bispécifiques) qui reconnaissent de manière spécifique C5aR1 et GM-CSFRα, et des compositions pharmaceutiques comprenant des anticorps multispécifiques (par exemple, bispécifiques) qui reconnaissent de manière spécifique C5aR1 et GM-CSFRα. L'invention concerne également des procédés de fabrication et d'utilisation de ces anticorps.