WO2024180452 - A METHOD FOR PRODUCING WETTABLE SILICONE HYDROGEL CONTACT LENSES

National phase entry:
Publication Number WO/2024/180452
Publication Date 06.09.2024
International Application No. PCT/IB2024/051822
International Filing Date 26.02.2024
Title **
[English] A METHOD FOR PRODUCING WETTABLE SILICONE HYDROGEL CONTACT LENSES
[French] PROCÉDÉ DE PRODUCTION DE LENTILLES DE CONTACT EN HYDROGEL DE SILICONE MOUILLABLES
Applicants **
ALCON INC.
Inventors
BREITKOPF, Richard Charles
JING, Feng
WU, Daqing
TRIEU, Jack W.
ZHANG, Steve Yun
Priority Data
63/487,046   27.02.2023   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2209
EPO Filing, Examination, Granting8765
Japan Filing, Examination, Granting2154
South Korea Filing, Examination, Granting2066
USA Filing, Examination, Granting4740
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Total: 19,934

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] The invention provides a method for producing coated silicone hydrogel contact lenses in a cost-effective manner. The method comprises treating the molding surfaces of polypropylene lens molds (or other hydrophobic plastic molds) with a vacuum UV or a corona plasma to increase the surface energies of the molding surfaces of the lens molds, cast-molding a silicone hydrogel lens formulation containing a relatively small amount of at least one carboxyl-containing vinylic monomer in the treated lens molds, and heating resultant cast-molded silicone hydrogel contact lenses in an aqueous coating solution comprising a water-soluble and thermally crosslinkable polymeric material to form a coated silicone hydrogel contact lens comprising a bulk silicone hydrogel material and a hydrogel layer covalently attached onto the bulk silicone hydrogel material.[French] L'invention concerne un procédé de production économique de lentilles de contact en hydrogel de silicone revêtues. Le procédé comprend le traitement des surfaces de moulage de moules de lentilles en polypropylène (ou d'autres moules en plastique hydrophobe) avec un UV du vide ou un plasma à effet corona pour augmenter les énergies de surface des surfaces de moulage des moules de lentilles, le moulage par coulée d'une formulation de lentille en hydrogel de silicone contenant une quantité relativement faible d'au moins un monomère vinylique contenant un carboxyle dans les moules de lentilles traités, et le chauffage des lentilles de contact en hydrogel de silicone moulées par coulée ainsi obtenues dans une solution de revêtement aqueuse comprenant un matériau polymère soluble dans l'eau et thermiquement réticulable pour former une lentille de contact en hydrogel de silicone revêtue comprenant un matériau d'hydrogel de silicone brut et une couche d'hydrogel fixée de manière covalente sur le matériau d'hydrogel de silicone brut.