WO2024116126 - OIL COMPOSITIONS WITH ENGINEERED LIPID PROFILES AND METHODS OF PRODUCING SAME
National phase entry is expected:
Publication Number
WO/2024/116126
Publication Date
06.06.2024
International Application No.
PCT/IB2023/062097
International Filing Date
30.11.2023
Title **
[English]
OIL COMPOSITIONS WITH ENGINEERED LIPID PROFILES AND METHODS OF PRODUCING SAME
[French]
COMPOSITIONS D'HUILE À PROFILS LIPIDIQUES MODIFIÉS ET LEURS PROCÉDÉS DE FABRICATION
Applicants **
MARA RENEWABLES CORPORATION
Inventors
RASMUSSEN, Holly
WOODHALL, David
BENJAMIN, Jeremy
MUISE, Denise
ARMENTA, Roberto E.
Priority Data
63/429,852
02.12.2022
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
| * | |
| Number of Office Actions | * |
| * | |
International Searching Authority |
CIPO
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
* |
| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Patent Delivery |
Send the Letters Patent by Courier
* |
| 译文 |
|
* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 4245 | |
| EPO | Filing, Examination, Granting | 53416 | |
| Japan | Filing, Examination, Granting | 3921 | |
| South Korea | Filing, Examination, Granting | 5821 | |
| USA | Filing, Examination, Granting | 15790 |
Total:
83,193
The term for entry into the National Phase has expired. This quotation is for informational purposes only
Contact Us
Abstract[English]
Provided herein are engineered microorganisms comprising one or more genes involved in fatty acid metabolism. For example, provided is an engineered microorganism comprising a first nucleic acid sequence encoding an elongase and a second nucleic acid sequence encoding a desaturase, wherein the first and second nucleic acid sequences are operably linked to promoter. Also provided are methods of making and using the engineered microorganisms. Also provided are microbial oils comprising fatty acids, wherein the fatty acids comprise C20:3(n-6) (di-homo-γ-linoleic acid) and C20:5(n-3) eicosapentaenoic acid (EPA). In addition, provided herein are methods of promoting conversion of saturated fatty acids to unsaturated fatty acids by transforming microorganisms with nucleic acid encoding polypeptides involved in the fatty acid synthesis pathway to generated increased conversion of saturated fatty acids to unsaturated fatty acids.[French]
L'invention concerne des micro-organismes modifiés comprenant un ou plusieurs gènes impliqués dans le métabolisme des acides gras. Par exemple, l'invention concerne un micro-organisme modifié comprenant une première séquence d'acide nucléique codant pour une élongase et une deuxième séquence d'acide nucléique codant pour une désaturase, les première et deuxième séquences d'acide nucléique étant fonctionnellement liées à un promoteur. L'invention concerne également des procédés de fabrication et d'utilisation des micro-organismes modifiés. La présente invention concerne également des huiles microbiennes comprenant des acides gras, dans lesquelles les acides gras comprennent l'acide C20:3(n-6) (acide di-homo-γ-linoléique) et l'acide C20:5(n-3) eicosapentaénoïque (EPA). En outre, La présente invention concerne des procédés pour favoriser la conversion des acides gras saturés en acides gras insaturés en transformant des micro-organismes avec des acides nucléiques codant pour des polypeptides impliqués dans la voie de synthèse des acides gras afin de générer une conversion accrue des acides gras saturés en acides gras insaturés.