WO2023187599 - METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES

National phase entry:
Publication Number WO/2023/187599
Publication Date 05.10.2023
International Application No. PCT/IB2023/052993
International Filing Date 27.03.2023
Title [English] METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES [French] PROCÉDÉS ET COMPOSÉS HAUTEMENT PERMÉABLES BIODISPONIBLES POUR LE TRAITEMENT DE MALADIES VIRALES
Applicants ** DIDENKO, Kirill 10685-B Hazelhurst Dr. # 31320 Houston, Texas 77043, US
Inventors ** DIDENKO, Kirill 10685-B Hazelhurst Dr. # 31320 Houston, Texas 77043, US
Priority Data 63/324,087  27.03.2022  US 63/398,038  15.08.2022  US
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Abstract [English] Provided are methods and compounds for treating virus infections by administering avermectin-based bioavailable highly permeable solid dispersions or solutions, suspensions or emulsions thereof. The compounds, compositions, and methods provided are particularly useful for the treatment of SARS-CoV-2, dengue, chikungunya, yellow fever, Zika and other viral infections. [French] L'invention concerne des procédés et des composés pour le traitement d'infections virales par l'administration de solutions ou de dispersions de matières solides hautement perméables biodisponibles à base d'avermectine, ou de suspensions ou d'émulsions de celles-ci. Les composés, les compositions et les procédés décrits sont particulièrement utiles pour le traitement du SARS-CoV-2, de la dengue, du chikungunya, de la fièvre jaune, de l'infection par le virus Zika et d'autres infections virales.